ATP2A3

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ATP2A3

A gene on chromosome 17p13.3 that encodes a SERCA Ca2+-ATPase, an intracellular pump located in the sarcoplasmic or endoplasmic reticula of muscle cells, which catalyses the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscle contraction and relaxation.
References in periodicals archive ?
La SERCA3 es la menos entendida y se ha ubicado en algunos tipos de musculo liso.
Three different SERCA genes were identified-SERCA1, SERCA2, and SERCA3. SERCA is mainly represented by the SERCA2a isoform in the heart.
Molecular cloning analyses identified three different SERCA genes, SERCA1, SERCA2, and SERCA3, which encode at least five [Ca.sup.2+] pump isoforms (11, 15-17).