CXCL12(redirected from SDF-1a)
CXCL12A gene on chromosome 10q11.1 that encodes a stromal cell-derived alpha chemokine of the intercrine family which, once bound to its receptor, CXCR4, activates lymphocytes, an interaction that has been implicated in the metastasis of breast and other cancers.
CXCL12 mutations are associated with resistance to HIV-1 infections.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.