CCL5

(redirected from SCYA5)

CCL5

A gene on chromosome 17q11.2-q12 that encodes a cytokine that is a chemoattractant for monocytes, memory T helper cells and eosinophils. CCL5 triggers the release of histamine from basophils and activates eosinophils, is produced by CD8+ T cells and is a major HIV-suppressive factor. It binds to the chemokine receptor CCR5, and suppresses in vitro replication of R5 strains of HIV-1, which use CCR5 as a coreceptor.

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CCL8
CCR3
CCR-3
Human Immunodeficiency Disease and Acquired Immunodeficiency Syndrome
RANTES

References in periodicals archive ?

It is well established that there are several other genes (such as SDF-1, SCYA5, K1R3, etc) involved in susceptibility to HIV-1 infection.

Association between inbreeding coefficient and susceptibility to HIV-1 infection, a case-control study

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