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Saethre-Chotzen syndrome

A craniosynostosis syndrome (OMIM:101400) characterised by coronal synostosis, brachycephaly, low frontal hairline, facial asymmetry, hypertelorism, broad halluces and clinodactyly; about half of female patients with Saethre-Chotzen syndrome eventually develop breast cancer.

Molecular pathology
Caused by defects of TWIST1, which encodes a basic helix-loop-helix (bHLH) transcription factor, and FGFR2, which encodes fibroblast growth factor receptor.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
'For instance, the law provides that SCs are entitled to 5% discount on their electric and water bills.
SCS has been awarded with the ESCA (European Secretariat for Cluster Analysis) Gold Label proving its gold standard excellence in terms of cluster management.
Gorely said Australia's approach and policy toward SCS has been very consistent over a long period of time.
Paul Devoy, head of Investors in People, said: "We'd like to congratulate SCS Group.
SCS Elite fits in virtually any size business aircraft, from turboprops to the heavy iron, and works across ATG and satellite systems.
Figure 3(a) shows logarithmic photo and dark J-V characteristics of [n.sup.+]p SC and [p.sup.+]n SC without BSF layer ([d.sub.BSF] = 0), and Figure 3(b) shows linear photo J-V characteristics of these SCs. Here the photocurrent was measured under AM1.5 light illumination.
Previously, several investigations reported that adult stem cells from adipose tissue can differentiate into SCs and promote neurite outgrowth in vitro [19-21].
A Microsoft Gold Certified partner with annual revenues of more than USD9 million, SCS specializes in Microsoft Dynamics NAV solutions.
The SCS also announced that the assistant honorary editor of the IJCS is Majella Lane, BSc PhD (UCL School of Pharmacy).
The Prodigy system is the only implantable spinal cord stimulation (SCS) system approved to deliver St.
The National Pain Report recently characterized the spinal cord stimulation (SCS) market as "crowded," which is not surprising when the current projections for market growth are so high.