SCN11A | definition of SCN11A by Medical dictionary
Also found in: Dictionary
SCN11A A gene on chromosome 3p22.2 that encodes a voltage-gated sodium ion channel, which is an integral membrane glycoprotein. It is responsible for the initial rising phase of the action potential in most excitable cells.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive
Caption: Figure 1: Locations and paralogue analysis of SCN11A variants associated with pain diseases in the Nav1.9 channel.
(%) NPHS2 V260E rs775006954 0.005 TTN T587Hfr11Ter NA NR SCN1A R604C rs148371904 0.002 SCN11A R838Q rs149681198 0.007 SPTBN4 R527W NA NR HSPG2 R2196W rs5 66319401 0.003 DSG L171F rs199926617 0.002 Variant impact prediction (b) Gene ACMG class Sift Mutation PolyPhen Tester NPHS2 Del.