4 years) was grafted to beige SCID mice
, and epidermal thickness, proliferation (Ki-67 expression), apoptosis (TUNEL [Tdt-mediated dUTP nick end labeling] reaction below granular layer), and expression of Fas and FasL were determined by histology and immunochemical staining.
Called severe combined immunodeficient mice, or SCID mice
, they have the equivalent of what is known as "bubble boy" disease.
Breeding diabetes scid mice
with streamline cabinet.
These included muscle weight increase in SCID mice
efficacy studies, muscle circumference changes in a 39-week toxicology study in monkeys, and total myostatin levels observed in multiple-ascending dose (MAD) studies in Phase I/II trials.
The paper highlights that human VSEL stem cells form human bone when implanted in the bone tissue of SCID mice
Methods: Human melanoma MV3 cells were subcutaneously xenografted into scid mice
, and pML-I or ML-I equivalent doses of Iscador M[R], respectively, were administered i.
Chinese red yeast rice inhibition of prostate tumor growth in SCID mice
A simple and rapid method to determine the zygosity of uPA-transgenic SCID mice
Furthermore, pre-clinical data from in vivo solid tumor models in SCID mice
(mice with deficient immune systems) show impressive anti-tumor effects induced by HuMax-ZP3.
Additionally, pre-clinical data from in vivo solid tumor models in SCID mice
(mice with deficient immune systems) show impressive anti-tumor effects induced by HuMax-ZP3, the company noted.
Indeed, preliminary studies have shown that no escape mutants emerged in SCID mice
treated with a combination of MAbs specific for M2e of wild-type PR8 and the P10H and P10L escape mutants (unpub.
Resistance of SCID mice
to Candida albicans administered intravenously or colonizing the gut: role of polymorphonuclear leukocytes and macrophages.