SARM


Also found in: Acronyms.

SARM

Selective androgen receptor modulators. A novel class of androgen receptor ligands. (The name follows the terminology currently used for similar molecules targeting the estrogen receptor, "selective estrogen receptor modulators," such as Tamoxifen.) They are intended to have the same kind of effects as androgenic drugs like anabolic steroids but be much more selective in their action, allowing them to be used for many more clinical indications than the relatively limited legitimate uses that anabolic steroids are currently approved for.

selective androgen receptor modulator

,

SARM

A class of medications that attach to cellular binding sites for male hormones. They are designed to maximize anabolic effects while limiting side effects. They may be used to treat conditions such as male hypogonadism or age-related bone loss.
References in periodicals archive ?
In an interview with XPRESS in November last year, Judge Bin Sarm said he did "not oppose capital punishment, as it is stated in our law.
In consideration for the SARM program license, Pharmacopeia will apply a portion of its medicinal chemistry resources to an unrelated Bristol-Myers Squibb discovery program for up to three years and pay Bristol-Myers Squibb milestone payments associated with submission and approval of a therapeutic product for marketing and a stepped royalty on net sales of therapeutic SARM products, if any, resulting from the SARM development program.
Andrew Sparrow during his recording session at Sarm West Studios in London
My clients did not touch the deceased," the trio's lawyer, Saeed Al Gailani, argued before presiding judge Bin Sarm.
Lt-Col Bin Sarm said that many of the fires reported recently in the emirate were due to some modifications or constructions done in the buildings without prior approval from the department.
Ligand has discovered several orally active, non-steroidal SARM compounds based on tissue-specific gene expression and other functional, cell-based technologies.
Initiation of this study represents a key milestone for Viking and our innovative SARM program as we work to rapidly advance the clinical development of VK5211," said Brian Lian, Ph.
Defending himself before presiding judge Saeed Salem Bin Sarm, K.
Khalfan Ali Mohammed bin Sarm, Secretary of the Tenancy Disputes Committee at the UAQ Municipality, said the cases filed involved 20 bounced cheques.
Others, including Spice Girls Mel C and Emma Bunton, Michael Owen, Katy B, Glenn Hoddle and Kimberley Walsh, packed into Sarm Studios, West London, where the 1984 Band Aid single was recorded.
SARM enables companies to not only gain visibility into the many different aspects of security information - from system configuration changes, to net flow patterns, to activity on servers, workstations, security and network devices, applications, and mobile devices - but also to understand how these different types of activity affect overall security and compliance posture.
The company's clinical programs include VK5211, an orally available, non-steroidal selective androgen receptor modulator, or SARM, entering Phase 2 development for the treatment and prevention of lean body mass loss in patients who have undergone hip fracture surgery, VK2809, a small molecule thyroid beta agonist entering Phase 2 development for hypercholesterolemia and fatty liver disease, and VK0612, a first-in-class, orally available drug candidate in Phase 2 development for type 2 diabetes.