PLK4

(redirected from SAK)
Also found in: Acronyms, Wikipedia.

PLK4

A gene on chromosome 4q27-q28 that encodes a member of the CDC5/Polo subfamily of serine/threonine protein kinases. PLK4 plays a central role in centriole duplication and is also involved in trophoblast differentiation by phosphorylating HAND1, which disrupts the HAND1/MDFIC interaction, leading to HAND1 activation. It also phosphorylates CDC25C and CHEK2. PLK4 is downregulated by p53/TP53.
References in periodicals archive ?
Using CIPP, SAK will rehabilitate 15,000 linear feet of sanitary sewer pipeline, with diameters ranging from 12 inches to 24 inches.
In other words, education would affect subjective norm, PU, PEU, and intention to use SAK ETAP.
A downgrade of Burgan bank AS's supported ratings could be triggered by a downwards rating action in the baseline standalone credit assessment(BCA) of Burgan SAK.
As such they have recruited expertise: Hyder Consulting has a good record, with local offices; also SAK Consultants has been there for 40 years.
Police leadership admitted on Friday that "there were some problems" but noted that Papageorgiou "referred the issue for study to a committee which SAK also participated in.
Aa He looks forward to the partnership with SAK and showed a strong desire to engage in discussions with interested parties.
Sparciuju SAK nusistovejimo trukmiu nustatyme sudaromi labai maza itampos verte (simtais ar maziau [micro]V) besiskiriantys nuo tiriamojo signalo nusistovejusiuju verciu atskaitos lygiai.
To minimize potential issues and to progress on schedule, SAK regulates the dry weather flow by using a combination of bypasses and flow diversions.
Country: TurkeySector: Banking/Financial ServicesTarget: Eurobank Tekfen ASBuyer: Burgan Bank SAK Vendor: Tekfen Holding AS , EFG Eurobank ErgasiasType: Corporate acquisitionFinancing: Existing resourcesStatus: AgreedComment: Price for the 70% stake is USD355m.
We've been working with these people for the last 30 years, which shows our clients come back to us," said Sheikh Solaiman El-Khereiji, chairman of SAK Consultants.
SAK has been a vocal critic of Papageorgiou's plans to reorganise the timetable for traffic police from a 12-hour shift to an eight-hour one.
Finnish trade union confederation SAK has reportedly demanded considerable wage increases in the upcoming comprehensive incomes policy agreement talks.