S100A11 | definition of S100A11 by Medical dictionary
S100A11 A gene on chromosome 1q21 that encodes a member of the S100 family of proteins, which contain 2 EF-hand calcium-binding motifs and as a group regulate cell cycle progression and differentiation and other cellular processes. The S100A11-encoded protein facilitates the differentiation and keratinocyte cornification, and may play a role in motility, invasion and tubulin polymerisation.
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References in periodicals archive
Expression of S100 proteins in normal human tissues and common cancers using tissue microarrays: S100A6, S100A8, S100A9 and S100A11
are all overexpressed in common cancers.
Amara et al., "The gene expression analysis of blood reveals S100A11
and AQP9 as potential biomarkers of infective endocarditis," PloS One, vol.
On the other hand, PPAR[gamma], CEBP[alpha], MAEL, TMEM60, S100A11
, and DPYD genes have a negative relationship with PC2.