Schistosoma mansoni

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Schistosoma

 [shis″-, skis″to-so´mah]
a genus of trematodes, including several species parasitic in the blood of humans and domestic animals. The organisms are called schistosomes or blood flukes. Larvae (cercariae) enter the body of the host by way of the digestive tract, or through the skin from contact with contaminated water, and migrate in the blood to small blood vessels of organs of the intestinal or urinary tract; they attach themselves to the blood vessel walls and mature and reproduce. The intermediate hosts are snails of various species.
The life cycle of Schistosoma. From Mahon and Manuselis, 2000.
Schistosoma haemato´bium a species endemic in North, Central, and West Africa and the Middle East; the organisms are found in the venules of the urinary bladder wall, and eggs may be isolated from the urine.
Schistosoma japo´nicum a species geographically confined to China, Japan, and nearby countries; found chiefly in the venules of the intestine.
Schistosoma manso´ni a species widely distributed in Africa and parts of South America; the organisms are found in the host's mesenteric veins, and eggs may be found in the feces.

Schis·to·so·ma man·so·ni

a common species of trematode characterized by large eggs with a strong lateral spine and transmitted by planorbid snails of the genus Biomphalaria; causes schistosomiasis mansoni in humans in Africa, parts of the Middle East, South America, and certain Caribbean islands.

Schis·to·so·ma man·so·ni

(skis'tō-sō'mă man-sō'nī)
A common species of trematodes characterized by large eggs with a strong lateral spine and transmitted by planorbid snails of the genus Biomphalaria; causes schistosomiasis mansoni.

Manson,

Sir Patrick, English authority on tropical medicine, 1844-1922.
Schistosoma mansoni - a disease-causing parasite transmitted by snails.
Mansonella - a genus of filaria, widely distributed in tropical Africa and South America.
Mansonia - a genus of brown or black medium-sized mosquitoes.
Manson disease - Synonym(s): Schistosoma mansoni
Manson eye worm - a widely distributed spiruroid nematode parasite of fowl. Synonym(s): Oxyspirura mansoni
Manson pyosis - obsolete term for a superficial pyogenic infection. Synonym(s): pemphigus contagiosus
Manson schistosomiasis - Synonym(s): schistosomiasis mansoni
Manson syndrome - pulmonary obliterative arteriolitis.
Oxyspirura mansoni - Synonym(s): Manson eye worm
schistosomiasis mansoni - infection with Schistosoma mansoni. Synonym(s): intestinal schistosomiasis; Manson disease; Manson schistosomiasis
References in periodicals archive ?
An acute form, called Katayama's fever, can develop within weeks of infection by S mansoni and S japonicum, and is characterised by abdominal pains, cough, fever, fatigue and diarrhoea.
Though schistosomiasis is endemic throughout much of the tropics in Africa, Asia and South America, three species of the parasite, S haematobium, Sjaponicum, and S mansoni are the known culprits associated with the cerebral form of the disease, and about 4% of patients infected with mansoni develop cerebral complications.
In the target-rich environment of the liver, the parasites begin to feed on red blood cells, with S mansoni and S japonicum developing elaborate oral sucker processes to do so.
Though schistosomiasis is endemic throughout much of the tropics in Africa, Asia and South America, three species of the parasite, S haematobium, S japonicum, and S mansoni are the known culprits associated with the cerebral form of the disease, and about 4% of patients infected with mansoni develop cerebral complications.
sativa crushed seeds against different developmental stages of S mansoni infection, at the time of infection (immature schistosomula < 14 days post infection), during schistosomula maturation (14-21 days Pi), at the time of schistosomula maturation (>21days PI) and after the beginning of egg laying (>35 days PI) (Davies et al.
Cercariae of an Eygptian strain of S mansoni were obtained from SBSP/TBRI and used for infection immediately after shedding from Biomphalaria alexandrina snails.
Group 1: Uninfected native control, Groups 2-6: S mansoni infected mice and classified as follow: Group 2: S mansoni-infected animals (positive control), Group 3: infected-N sativa treated group immediately at the time of infection (immature schistosomula < 14 days post infection).
The result revealed that oral administration of N sativa seeds to S mansoni infected mice (Gs 3, 4, 5 & 6) showed significant reduction of all forms of differential worm burden, the solitary male and female and coupled which is coincided with a decrease in the total egg burden (from liver) compared to untreated infected animals (G2).
The current study demonstrated that administration of N sativa crushed seeds to mice harboring S mansoni have shown potential antischistosomal activity against the different developmental stages of thee parasites, immature larveae (schistosomula, < 14 days Pi, G3), during schistosomula maturation (14-21 days PI,G4), at the time of schistosomula maturation (>21days PI,G5) and after the beginning of egg laying (>35 days PI,G6) (Davies et al.
One of the major pathological features of S mansoni parasites is their ability to persist and establish a chronic infection.
Similar result was obtained by some authors who emphasized that elevated liver hydroxyproline content was associated with S mansoni infection (Marck, 2005; Metwally, 2006) and this may be attributed to that S mansoni egg granulomas contain factors responsible for the elevation of free L-hydroxyproline content in the fibrotic liver (Adewusi et al.
Elevated level of AFP in sera of S mansoni infected animals presented in the current study may be considered as an index for liver fibrosis related to schistosomiasis.