The poorly digestible carbohydrates, such as nonstarch polysaccharides, resistant starch, nondigestible oligosaccharides (NDOs), and polyphenols, are source of various sugars including glucose, galactose, rhamnose, and rutinose
. The carbohydratehydrolyzing enzymes of colonic microbiota promote the fermentation of prebiotics, and these produce hydrogen, methane, carbon dioxide, and SCFAs.
A fragment ion at m/z 447 was more obvious in peak 10 (8%) than in peak 11, which implied that the disaccharide was deduced to be neohesperidose in peak 10 and rutinose
in peak 11, respectively.
Quercetin and one of its glucosides, quercetin-3-0 rutinose
(rutin), are among the most abundant flavonoids in vegetables and fruits (Aherne and O'Brien.
Rutin, a flavonoid composed of flavonol quercetin and disaccharide rutinose
, has anti-inflammatory, hypotensive effect.
Rutin, comprising quercetin and disaccharide rutinose
, is a member of flavonoids also called vitamin P present in Herba Leonuri.
A cianidina 3-rutinosideo (pico 2) apresentou ion molecular a m/z 595 e dois fragmentos a 287 e 449 u, o primeiro fragmento correspondendo a aglicona cianidina, como resultado da perda de rutinose
(308 u), e o fragmento a m/z 449 correspondendo a aglicona cianidina mais uma molecula de hexose, como o resultado da perda de uma desoxi-hexose [[M-146].sup.+].
Other sugars involved are glucose, rhamnose, xylose, arabinose and the disaccharide rutinose
. Unlike other flavonoids, flavan-3-ols are generally found in the free rather than in the glycosylated forms.
The compound in fescue eluting at RT = 19.5 min was isolated as described above and on acid hydrolysis yielded rhamnose, glucose, rutinose
, and quercetin as determined by GC and HPLC co-elution with authentic standards indicating the compound as rutin.
Rutin is a flavonol glycoside composed of quercetin and the disaccharide rutinose
Rutin (also known as vitamin P or rutoside) is a flavonol glycoside found in many plants and fruits , resulting from the combination of the flavonol quercetin and the disaccharide rutinose
. Indeed, upon oral administration, the disaccharide is cleaved, and quercetin is liberated, so that rutin's anti-inflammatory actions appear to be due to the quercetin-mediated effects via the inhibition of the proinflammatory chain triggered by TNF-[alpha]-induced NF-[kappa]B activation .
As the only difference between diosmin and the diosmetin is the rutinose
moiety present on diosmin (Fig.