These were then evaluated for histopathological variables which included thickness of epithelial lining, keratinization, foamy macrophages, mucous cells, Rushton bodies, cholesterol crystals and haemosiderin.
The cystic lesions were then evaluated for histopathological variables which included presence or absence of keratinization, cytological atypia and tumour arising within cyst lining, foamy macrophages, mucous cells, vacuolated cells, Rushton bodies, spongiosis , ciliated cells , necrosis, micro-abscesses and Russel bodies, cholesterol crystals, hemosiderin and inflammatory infiltrate.
Other features like cytological atypia, tumour arising within cyst lining, foamy macrophages, Rushton bodies, Russel bodies, ciliated cells and necrosis and were not found in any of the selected samples.
The inflamed cyst shows a much thicker, proliferative epithelium, with hyperplastic rete, chronic inflammation (figure 2), and sometimes hyalinized keratin (Rushton bodies
These Rushton bodies were positive with Papanicolaou (PAP) & Masson's Trichrome stains.
Based on clinical, radiological and histopathological findings, diagnosis of "radicular cyst with Rushton bodies" was made.
Rushton bodies within the epithelium in odontogenic cyst were first described in detail by MA Rushton and hence are often referred to as Rushton bodies.6 These hyaline bodies are found in approximately 10% of periapical cysts.
Microscopically, on histopathological examination Rushton bodies appear as structures tucked within the epithelium that are acellular, eosinophilic, linear, straight or curved or hairpin shaped, circular or polycyclic forms often with a granular core and at times laminated concentrically.
Rushton bodies give negative result with Periodic acid Schiff and Von Kossa's stains for mucopolysaccharides and calcium respectively.
According to Rushton, Rushton bodies originated from odontogenic epithelium as a keratin product.
In our case, Rushton bodies within the epithelial lining appeared as acellular, eosinophilic and curvilinear shaped structures.
(refractile, brightly hypereosinophilic, curvilinear hyaline keratin bodies) may be seen (figure 4), but are not specific to this entity.