Contemporary diagnosis and management of preterm premature rupture of membranes
. Rev Obstet Gynecol 2008;1(1):11-22.
Influence of premature rupture of membranes
on neonatal health.
Meta-analysis of studies on biochemical marker tests for the diagnosis of premature rupture of membranes
: Comparison of performance indexes.
Seventeen percent of the women had the rupture of membranes
confirmed by digital per vaginam examination despite the leakage of fluid having been noted in the patient history.
Therefore, nine (90%) women should have received IAP, according to the protocol (three had premature labor; one had premature labor and rupture of membranes
[greater than or equal to]18h; four had premature labor, rupture of membranes
[greater than or equal to]18h and fever during labor; and one had premature labor and fever during labor); however, only five (55.5%) received antibiotics during labor: four received clindamycin for presumed chorioamnionitis, and one received ampicillin as prophylaxis, according to protocol, because she had a preterm labor and rupture of membranes
[greater than or equal to]18h.
Although this study was not powered to determine associated factors, it was noted that there were more positive cultures when the duration of rupture of membranes
was longer than 24 hrs but this result was not statistically significant; P = 0.055.
Preterm premature rupture of membranes
(PPROM)--when rupture of membranes
occurs before 37 weeks' gestation--affects about 3% of all pregnancies in the United States, and is a major contributor to perinatal morbidity and mortality.
Immediate delivery compared with expectant management after preterm pre-labour rupture of membranes
close to term (PPROMT trial): a randomized controlled trial.
Induction in pre labour rupture of membranes
could be done both with Prostaglandin and Oxytocin9.
Aim of our study is therefore to compare the effects of induction of labor with PGE2 versus expectant management, on maternal and fetal well-being, in women with term prelabor rupture of membranes
. This comparative study was conducted in an attempt to reduce the maternal and neonatal morbidity due to complication of PROM and to improve maternal and fetal outcome and if it proves that management outcome of induction of labor in term PROM is better than expectant management, it will be helpful in 1) avoiding unnecessary delay awaiting spontaneous onset of labor, 2) better maternal outcome in terms of lesser cesarean deliveries and lesser cases developing chorioamnionitis and 3) better neonatal outcome in terms of better APGAR scores and lesser cases of neonatal sepsis.
Elective caesarean delivery coupled with ZDV prior to the onset of labour and rupture of membranes
significantly decreases vertical HIV transmission in women (35,36).