- The author estimates that in 2017, there were approximately 113.2 million (NIH criteria) to 188.7 million (Rotterdam criteria
) prevalent cases of polycystic ovary syndrome (PCOS) in females aged 15-49 years worldwide, and expects that number to increase to between 119.5 million (NIH criteria) and 199.1 million (Rotterdam criteria
) by 2026.
The Rotterdam criteria
require any two of the following three conditions for diagnosis: anovulation/oligoovulation, hyperandrogenism, and polycystic ovaries revealed by sonogram.
Controversy in clinical endocrinology: Diagnosis of polycystic ovarian syndrome: The rotterdam criteria
Seventy women aged between 15 and 45 years diagnosed as PCOS according to Rotterdam criteria
, and 70 otherwise healthy, non-hirsute women in the same age group who had normal menstrual cycles and PCOM on ultrasonography were included in the study.
They were screened for the presence of polycystic ovarian syndrome (PCOS) by using Rotterdam criteria
Efforts at generating consensus have been an ESHRE/ASRM initiative, leading to the 2003 Rotterdam criteria
for the diagnosis of PCOS.
Patients with stage IIIa disease were high-risk, with sentinel node tumors exceeding 1 mm diameter per Rotterdam criteria
. Stage IIB or IIIC patients had no in-transit metastases.
"This study demonstrated that Caucasian women diagnosed with PCOS using the Rotterdam criteria
had a reduction in overall species richness [alpha diversity] of the gut microbiome, compared to healthy women, and changes in the composition of the microbial community [beta diversity]" wrote Pedro J.
There is an exception to the Rotterdam criteria
, as recently discussed in the literature.
The diagnosis of PCOS was arrived based on history, clinical signs, physical examination, laboratory parameters, and ultrasound findings, as per Rotterdam criteria
 (Table I) by the Gynaecologist.
In 2003 Rotterdam criteria
was used to diagnose PCOS: 1- oligomenorrhea-amenorrhea, 2- biochem- ical and/or clinical hyperandrogenism and 3- PCO morphology in ultrasonography (USG).
According to the so-called Rotterdam criteria
, a woman with any two of the following may have the condition: