Rotashield

Rotashield

(rōt′ă-shēld″)
Trade name for a rotavirus vaccine that was withdrawn from the market because of its association with intussusception of the bowel.
References in periodicals archive ?
In 1999, the Rotashield rotavirus vaccine was removed from the US market due to its increased association with i ntu ssusception, especially between 3-14 days post-placement of the vaccine.
Remember the Wyeth rotavirus vaccine, RotaShield, which was withdrawn after a little more than a year on the market?
Reassortment of animal rotavirus segments onto human strain backbones has been documented (28), and experimental insertion of human rotavirus strains onto animal strain backbones was the basis for construction of reassortant rotavirus vaccines Rotashield and RotaTeq (29).
Ilk reassortant rotavirus asisi olan tetravalan maymun-insan reassortant rotavirus asisi (RRV-TV, Rotashield, Wyeth-Lederle), ABD'de 31 Agustos 1998'de ruhsat almis ve 1999 yili rutin asi semasina dahil edilmistir.
The first, RotaShield, was removed from the market in 1999 because of a detected increase in intussusceptions.
More on RotaShield and intussusception: the role of age at the time of vaccination.
The best example for this is the RotaShield vaccine for rotavirus, which was pulled from global circulation in 1999 by Wyeth-Ayerts Labs, the holder of the exclusive license, following the reporting of a small number of cases of intestinal blockage.
14) The withdrawal of RotaShield by the FDA led to an intense international debate over whether the apparently small increase in the risk of intussusception should prevail over what would likely have been a much larger reduction in morbidity and mortality in the developing world.
The earlier vaccine, Wyeth's RotaShield, was pulled from the U.
government approved the vaccine, which Wyeth named RotaShield.
In the summer of 1998 Rotashield, a vaccine for rotavirus, was introduced and infant immunizations were started.