ricinine


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ri·cin

(rī'sin)
Toxin derived from castor beans that causes inflammation of the gastrointestinal mucosa and the respiratory tract.
[L. ricinus, castor oil plant]

ricinine

(rĭs′ĭn-ĕn) (-īn)
A poisonous alkaloid present in the leaves and seeds of the castor bean plant, Ricinus communis.
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References in periodicals archive ?
The Fe chelation by ricinine was investigated by the method described by Dinis et al.
Ethyl acetate fraction, reddish brown clear crystals after X-ray crystallographic studies was identified as ricinine (1,2-dihydro-4-methoxy-1-methyl-2-oxo-3-pyridinenitrile), an alkaloid already reported in literature.
Under optimized conditions IC50 value for anti-AChE activity was calculated from caliberation curve constructed in concentration range of 10-132 ug/ml of ricinine. Results of our study demonstrate that ricinine is a potent inhibitor of the enzyme with IC50 value of 54.5ug/ml (Fig.
When we look at the structural chemistry of ricinine, binding with anionic site through quartarnary nitrogen and binding with both anionic and esteric sites due to the presence of quartarnary nitrogen and carbonyl carbon is expected.
However, rapid reactivation of AChE inhibited with ricinine in a stream of (pH 8.5) shows that enzyme-inhibitor complex is unstable and easily hydrolysable.
Therefore, in this study we have investigated antioxidant activity of ricinine by its free radical scavenging potential.