Richter syndrome

Rich·ter syn·drome

(rik'tĕr),
a high-grade lymphoma developing during the course of chronic lymphocytic leukemia; associated with cachexia, pyrexia, dysproteinemia, and lymphomas with multinucleated tumor cells.

Richter syndrome

The development of a clinically aggressive pleomorphic large–usually B cell–lymphoma in the background of CLL–which occurs in 3-10% of CL or Waldenström's macroglobulinemia Clinical Rapid onset of intractable fever, weight loss, lymphadenopathy, hepatosplenomegaly

Rich·ter syn·drome

(rik'ter sin'drōm)
A high-grade lymphoma developing during the course of chronic lymphocytic leukemia; associated with cachexia, pyrexia, dysproteinemia, and lymphomas with multinucleated tumor cells.

Richter,

Maurice N., U.S. pathologist, 1897–.
Richter syndrome - a high-grade lymphoma developing during the course of chronic lymphocytic leukemia.
References in periodicals archive ?
Richter syndrome is defined as the development of a large cell lymphoma in patients with chronic lymphocytic leukemia, and this transformation is characterized by rapid deterioration in the patient's general condition, lymphadenopathy, and hepatosplenomegaly.