ribonucleotide reductase

(redirected from Ribonucleotide reductases)

ri·bo·nu·cle·o·tide re·duc·tase

a protein complex that converts ribonucleotide diphosphates (NDPs) such as ADP and CDP to 2'-deoxyribonucleotide diphosphates (dNDPs) such as dADP and dCDP. This complex requires thioredoxin, thioredoxin reductase, and NADPH. It is crucial for DNA synthesis.

ribonucleotide reductase

(1) Ribonucleoside-diphosphate reductase, EC 1.17.4.1. 
(2) Ribonucleoside-triphosphate reductase, EC 1.17.4.2.
References in periodicals archive ?
Ribonucleotide reductases from other organisms fall into three distinct categories, based on their amino acid sequences and biochemical functions.
That enzyme, ribonucleotide reductase, converts the building blocks of RNA into the building blocks of DNA.
"The term is over-used, but it really does apply." The modern forms of the ribonucleotide reductase probably evolved from some- thing similar to the P.