The partnership will develop and commercialise its poly-N-acetyl glucosamine (PNAG) vaccine for Rhodococcus equi
(previously known as Corynebacterium equi) is a gram positive, obligately aerobic, intracellular coccobacillus that establishes itself in macrophages by interfering lysophagosomal fusion and multiplies within macrophages; lead to formation of granulomas and eventually necrosis (Prescott, 1991).
It can be seen from Figure 2 that the strain is compatible with Rhodococcus equi
. The genetic distance is the closest, and it can be preliminarily determined that the strain belongs to Rhodococcus.
Mucosal co-immunization of mice with recombinant lactococci secreting VapA antigen and leptin elicits a protective immune response against Rhodococcus equi
(2003) identified Rhodococcus equi
in the horse conjunctiva in five samples, representing only 0.2% of the total isolates.
Antibiotic failure in a renal transplant patient with Rhodococcus equi
infection: an indication for surgical lobectomy.
(GA11), Bacillus anthracis, Bacillus cereus, Bacillus subtilis, Corynebacterium sp., Escherichia coli, Klebsiella pneumoniae (GA15), Listeria ivanovii ATCC19119, Listeria monocytogenes ATCC19111, Rhodococcus equi
, Salmonella Enteritidis, Streptococcus pyogenes, Streptococcus pneumoniae, and three clinical isolates of Methicillin-resistant Staphylococcus aureus (MRSA).
from human clinical specimens by sequencing the 16S rRNA genes and performing biochemical analysis (CAMP test) on isolates initially classified as Rhodococcus equi
is an aerobic, Gram-positive, nonspore forming coccobacillus which infects foals within the first few weeks of life and can cause severe pyogranulomatous pneumonia between 1 and 6 months of age [1-3].
pseudotuberculosis se aplicaron las pruebas de fermentacion de carbohidratos (maltosa, trehalosa, glucosa, sacarosa, xilosa, galactosa, arabinosa, manitol y fructosa), reduccion de nitratos, produccion de hemolisina, pruebas CAMP sinergico con Rhodococcus equi
e hidrolisis de varios compuestos (urea, almidon, gelatina nutritiva y caseina) [10, 20, 21, 30, 41,46, 47, 53, 63, 68].
However, on January 27, 2011, Intervet/Schering-Plough Animal Health announced that a vaccine against Rhodococcus equi
infection in foals had entered the final stages of development .