Rh incompatibility


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Related to Rh incompatibility: Rh factor, Rhogam, Coombs test, ABO incompatibility

Rh incompatibility

the agglutination (clumping together) of red blood cells as a result of mixing different antigens (agglutinogens) present on the surface of the cells. This agglutination is an immune reaction and depends on the formation of antibodies against the specific agglutinogen (Rh factor) present on the red blood cells and in blood from a transfusion or fetal tissues. The immune reaction does not occur immediately, but depends on the gradual formation of antibodies. For example, a D-negative (Rh negative) person who has been previously exposed to D-positive red cells through transfusion or pregnancy may produce anti-D, and therefore be incompatible with all D-positive (Rh positive) red cells. See also Rh factor.

Rh incompatibility

 Transfusion medicine An incompatibility in Rh types between a donor and recipient, or between an fetus–who is Rh positive, and the mother–who is negative and produces antibodies against the fetus' RBCs, which pass to the placenta, and cause HDN. See Hemolytic disease of the newborn.

Rh incompatibility,

n a condition in which two groups of blood cells are antigentically different because of the presence of Rh factor in one group and the absence of the Rh factor in the other. See also Rh factor.
References in periodicals archive ?
Conclusions: Knowledge about blood groups, Rh incompatibility and its complications during pregnancy and after child birth was very low and needs to be addressed through public education.
Questionnaire included information on maternal and child health, complications of Rh incompatibility during and after pregnancy, its risk to new born, prevention of Rh disease, consultation of health care providers during pregnancy and number of visits tohealth care centre during pregnancy etc.
Independent studies of Rh incompatibility and schizophrenia are under way, according to Hollister's group.
Genes determine whether an individual possesses RhD-positive or RhD-negative antigens, so Rh incompatibility probably clusters in some families.
We should take necessary steps to prevent Rh incompatibility by providing appropriate antenatal care consisting of administration of Anti-D Immunoglobulin to unsensitised Rh negative mothers.
G6PD deficiency was encountered as the most common cause (23%) followed by ABO incompatibility (20%), Rh incompatibility (16%), preterm (14%), exaggerated physiological (12%), sepsis (10%), miscellaneous (7%).
CONCLUSION: G6PD deficiency and ABO incompatibility were commonest causes requiring exchange transfusion followed by Rh incompatibility, preterm, exaggerated physiological, sepsis, miscellaneous causes.
In present study total number of cases of placental grade-II is 66 cases out of which 2 cases of anemia, 1 case of APH, one case BOH, one case breech, 2cases of hypothyroidism, 3 cases oligohydramnios, 5 cases pre-eclampsia, 2 cases poly hydramnios, 1 case post datism, 3 cases of previous section 5 cases of PROM, 1 case of Rh incompatibility, 3 cases of twins and 36 cases without any risk factor.
Serologicals provides value-added, antibody-based products that are used as the active ingredients in therapeutic products for the treatment and management of diseases such as Rh incompatibility in newborns, rabies and hepatitis and in diagnostic products such as blood typing reagents and diagnostic test kits.
There was no history of Diabetes, Hypertension, RH incompatibility and TORCH group of infections.
The Company provides value-added, antibody-based products that are used as the active ingredients in therapeutic products for the treatment and management of diseases such as Rh incompatibility in newborns, rabies and hepatitis and in diagnostic products such as blood typing reagents and diagnostic test kits.
The Company provides value-added antibody-based products that are used as the active ingredients in therapeutic products for the treatment and management of diseases such as Rh incompatibility in newborns, rabies and hepatitis and in diagnostic products such as blood typing reagents and diagnostic test kits.