Rh blood group


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Rh fac·tor

(fak'tŏr)
A protein substance present in the red blood cells of most people (85%), capable of inducing intense antigenic reactions. A person who has the protein substance is calledRh-positive and a person who does not have the protein substance is called Rh-negative. Under ordinary circumstances, the presence or lack of the Rh factor has no bearing on life or health, except when the positive and negative forms commingle. The Rh factor was first identified in the blood of the rhesus monkey in 1940.
Synonym(s): Rh blood group, Rhesus factor.

Rh blood group

A group of antigens on the surface of red blood cells present to a variable degree in human populations. When the Rh factor (an antigen often called D) is present, an individual's blood type is designated Rh+ (Rh positive); when the Rh antigen is absent, the blood type is Rh- (Rh negative). If an individual with Rh blood receives a transfusion of Rh+ blood, anti-Rh antibodies form. Subsequent transfusions of Rh+ blood may result in serious transfusion reactions (agglutination and hemolysis of red blood cells). A pregnant woman who is Rh may become sensitized by entry of red blood cells from an Rh+ fetus into the maternal circulation after abortion, ectopic pregnancy, or delivery. In subsequent pregnancies, if the fetus is Rh+, Rh antibodies produced in maternal blood may cross the placenta and destroy fetal cells, causing erythroblastosis fetalis.
See: Rh immune globulin
See also: blood group
References in periodicals archive ?
Association of diabetes mellitus with ABO and Rh blood groups. Ann Pak Inst Med Sci 2012; 8: 134-6.
Soboyejo, "Frequency distribution of ABO, RH blood groups and blood genotypes among the cell biology and genetics students of University of Lagos, Nigeria," African Journal of Biotechnology, vol.
The association of ABO and Rh blood groups with various diseases, such as cancer, cardiovascular disorders, infections, and diabetes mellitus, has been demonstrated (11-14).
Distribution of ABO and Rh Blood Group Alleles in Sahiwal district of the Punjab, Pakistan.
Review: The Rh blood group system: an historical calendar.
Rh Blood group system: the D antigen and high and low frequency Rh antigens.
Among the 165 babies 81 (41%) of babies had no blood group incompatibility with mother, 47 (28.5%) of babies has OA incompatibility with mother, 24 (14.5%) cases had OB incompatibility with mother and 13 (7.9%) babies had Rh blood group incompatibility with mother.
ABO and Rh blood group markers have been extensively characterized in human populations across the globe.
Molecular techniques have enabled rapid developments in the field of immunohematology, building on the early-twentieth century identification of blood groups A, B, O, and AB and identification of the Rh blood group system in the 1940s.
Contract notice: AB0 blood group determination, as well as to obtain the necessary AB0 and Rh blood group determination of Bedside cards.
It has proved very effective for identifying fetal genetic loci completely absent from the maternal genome, such as those on the Y chromosome or the RHD [3] (Rh blood group, D antigen) gene (2).