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1. A transposition of sequences in a DNA that does not originate in the DNA but rather in an mRNA that is transcribed back into the genomic DNA by reverse transcription. Synonym(s): retrotransposon
2. A transposable element.
[retro- + L. pono, pp. positum, to place, + -on]


A transposon copied from RNA with the use of reverse transcriptase.


a type of TRANSPOSABLE GENETIC ELEMENT, found in eukaryotic genomes, that utilizes RNA as an intermediate and the enzyme REVERSE TRANSCRIPTASE to transpose. Reverse transcription of the RNA transcripts of the transposon produces a DNA copy that subsequently inserts into the GENOME to effect transposition. Retrotransposons may be degenerate RETROVIRUSES.

retrotransposon, retroposon

a mobile sequence of DNA that transposes via a RNA intermediate.
References in periodicals archive ?
The first authors of the paper, postdoctoral researcher Frank Jacobs and graduate student David Greenberg, came up with the strategy of testing primate retrotransposons in non-primate cells by using mouse embryonic stem cells that contain a single human chromosome.
Retrotransposons are short sequences of DNA that autonomously amplify and move around the genome.
Ty-lcopia group retrotransposons are ubiquitous and heterogeneous in higher plants.
Retrotransposons can be divided into two distinct groups; those containing longterminal repeats (LTRs) and others (so-called non-LTR retroelements).
A relatively new phylogenetic tool involves short interspersed DNA elements (SINEs), which are groups of non-autonomous retrotransposons that are abundant in many mammalian genomes.
Researchers hypothesize that retrotransposons derived from viruses that infected cells early in animal evolution.
Its relationship to retrotransposons, a class of mobile genetic elements that shares similarities with telomerase and serves as telomeres in selected organisms, are also reviewed.
Therefore, retrotransposons could be also considered as attractive endogenous source of genetic variation.
Tandem repeats and retrotransposons have been conveniently converted into a "plus" or "minus" sign--a red light/green light clinical decision.
Retrotransposons are travelling bits of DNA that replicate by copying and pasting themselves at new locations in the genome.