retinoic acid receptor

(redirected from Retinoid receptors)

retinoic acid receptor

nuclear receptor for retinoic acid.
Farlex Partner Medical Dictionary © Farlex 2012

ret·i·no·ic ac·id re·cep·tor

(ret'i-nō'ik as'id rĕ-sep'tŏr)
Nuclear receptor for retinoic acid.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Melanocytes express some retinoid receptors that are lost in melanoma compared to benign nevi [18], which could be a direct cause of vitiligo in this case.
Granactive Retinoid is unique in that it processes innate retinoic activity, binding directly with retinoid receptors without the need for metabolic breakdown to more biologically active forms, said the company.
EvainBrion, "The expression of nuclear retinoid receptors in human implantation," Placenta, vol.
This superfamily also possesses steroid hormone receptors, vitamin D, retinoid receptors and orphan receptors.
Isotretinoin is a non-selective retinoid, with actions at all retinoid receptors, a, b and g, while adapalene has no action on a receptors.
A further indication that the receptor-binding pathway is strongly involved in retinoid dermatitis is the finding that genetically engineered mice born deficient in nuclear retinoid receptors develop neither epidermal hyperplasia nor skin irritation after the application of topical tretinoin.
Retinoid receptors belong to a superfamily of ligand-inducible transcription factors including steroid, vitamin D, thyroid hormone, peroxisome proliferator-activated receptor, and orphan receptors with unknown functions [14].
Adipose tissues have long been recognized as potential sites for RA action, and where retinoid receptors of two different subfamilies (RAR and RXR) are expressed (Haq and Chytil, 1991; Kamei et al., 1993).
Preliminary results show that cholecalciferol u pregulares vitamin D and certain retinoid receptors, inhibits growth and invasion, induces differentiation, and decreases the expression of proteins associated with malignant transformation.
Natural retinoids are isomerized to various molecules in the skin, activating a host of retinoid receptors. Adapalene lacks this ability and therefore activates far fewer receptors.

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