E2F1

(redirected from Retinoblastoma-associated protein 1)

E2F1

A gene on chromosome 20q11.2 that encodes a member of the E2F family of DNA-binding transcription factors, which play a key role in regulating the cell cycle and tumour suppressor proteins. E2Fs are targets of transforming proteins of small DNA tumour viruses.
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Rb1 (retinoblastoma-associated protein 1) and HDAC2 (histone deacetylase 2) were involved in apoptosis, S-phase, and DNA biosynthesis [25].

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