retinal

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Related to Retinal degeneration: retinitis pigmentosa

retinal

 [ret´ĭ-nal]
1. pertaining to the retina.
2. the aldehyde of retinol, having vitamin A activity. One isomer (11-cis-retinal) combines with opsin in the retinal rods (scotopsin) to form rhodopsin (visual purple); another, all-trans-retinal, or visual yellow, results from the bleaching of rhodopsin by light, in which the 11-cis form is converted to the all-trans form. Retinal also combines with opsins in the retinal cones to form the three pigments responsible for color vision.

ret·i·nal

(ret'i-năl),
1. Relating to the retina.
2. Retinaldehyde, most commonly referring to the all-trans form; participates in the visual process; 11-cis-retinal binds with an opsin to form iodopsin or rhodopsin; light causes the formation of all-trans-retinal, which dissociates from the protein.

retinal 1

(rĕt′n-ăl′)
adj.
Of or relating to the retina of the eye.

retinal 2

(rĕt′n-ăl′, -ôl′)
n.
Either of two chromophores that are aldehydes of vitamin A1 and vitamin A2 and that bind covalently with an opsin protein to form rhodopsin or porphyropsin. Also called retinene.

retinal

adjective Referring to the retina noun 11-cis-retinal, vitamin A aldehyde A retinal pigment that absorbs visible light at 400-600 nm, resulting in an isomeric transition of the 11-cis-retinal moiety to a trans-retinal conformation causing a G protein-mediated depolarization event

ret·i·nal

(ret'i-năl)
1. Relating to the retina.
2. Retinaldehyde; most commonly referring to the all-trans form.

retinal

The aldehyde found in visual pigments, such as visual purple. Also known as retinaldehyde.

retinal 

1. Pertaining to the retina.
2. See rhodopsin.
References in periodicals archive ?
was founded in 1998 to create a retinal prosthesis to provide sight to patients blinded from outer retinal degenerations such as RP.
Peripheral retinal degenerations and retinal detachment
Dyer said that a particularly promising alternative was the possibility of taking samples of adult cells-such as fibroblasts that form connective tissue-from a patient with retinal degeneration and exposing them to genetic cues that induce them to revert to stem cells.
Therefore, in this study, we tested the effects of activating ERK1/2, P38, and JNK in a model of light-induced retinal degeneration. We also used specific MAPK antagonists, inhibitors of p-P38 (SB203580), p-ERK1/2 (U0126), and p-JNK (SP600125), to investigate the effects of MAPKs on photoreceptor degeneration and inflammation during light exposure.
Cell therapy for retinal degeneration diseases has recently gained attention.
Studies have shown an association between increased AL and the severity of myopia with peripheral retinal degeneration and an increased prevalence of peripheral retinal degeneration in myopia [17, 32-35].
Tsubura, "Morphologic characteristics of retinal degeneration induced by sodium iodate in mice," Current Eye Research, vol.
The signs of retinal degeneration were symmetrical for both eyes in each dog and severity of ophthalmoscopic fundus abnormalities was somewhat variable among affected dogs.
The technology was previously tested on mice in trials led by Paul Bishop, Professor of Ophthalmology at the University of Manchester and proved to be effective at restoring a visual response in a mouse model of retinal degeneration.
There is no citation in the literature regarding ERG findings in dogs with glaucoma and sudden acquired retinal degeneration. In Veterinary clinics, ERG is used to evaluate retinal function in animals with cataract, glaucoma, PRA, SARD and other conditions (Narfstrom et al., 2002).
[ClickPress, Wed Jul 29 2015] Global Markets Direct's, 'Retinal Degeneration - Pipeline Review, H1 2015', provides an overview of the Retinal Degeneration's therapeutic pipeline.
The University of Miami, Bascom Palmer Eye Institute investigated if a diet supplemented with grapes could protect the photoreceptors in mice with retinal degeneration, where the mice were either fed a grape-supplemented diet corresponding to 3 servings of grapes per day for humans or one of two control diets.