How do enhancers and repressors
work across such large distances--and perhaps more interestingly, how is it that they're specific?
ISOLATION, PURIFICATION, MODELING, AND BINDING SITE ANALYSIS OF THE SALMONELLA BACTERIOPHAGE [epsilon]34 REPRESSOR
FOR SUBSEQUENT CRYSTALLIZATION AND STRUCTURE-FUNCTION STUDIES.
Mathematical analysis of the kinetics of the lac repressor
operator interaction in the E.
We decided to analyze the whole transcriptional network, observe the number of transcription factors, calculate the RI for each gene, and obtain the overall activators and repressors
Our results agree with the assumption that SCO1678 encodes a repressor
of the gnt genes.
The UC Santa Cruz researchers have, for the first time, identified genes in humans that make repressor
proteins to shut down specific jumping genes.
However, when the expression level is high enough, it rather plays as a passive repressor
by competing CREB/CREM/ATF1 transcriptional activators for binding to CRE (Figure 2).
In the present study, therefore, our aim was to establish whether or not repressors
experienced fewer aversive images when using the TNT paradigm than when it was not used.
"We discovered that the Notch protein, which is involved in the development of most tissues, is responsible for activating the gene GATA2 which is necessary to generate hematopoietic stem cells; at the same time, it induces the reproduction of its own repressor
, HES-1," said Anna Bigas, the coordinator of the research group on stem cells and cancer at IM1M:
Although they might be at a higher risk of developing certain illnesses, recovery from a range of conditions appears to be faster among repressors
In the classic molecular genetic studies, prokaryotic promoters were believed to be regulated by a single specific regulatory protein, either a repressor
and an activator, as originally identified in the lac operon regulation by LacI repressor
"Many former repressors
continue fulfilling official functions in the police and military security forces," said Teresita Asilvera, a CCS leader.