Renshaw cells

Ren·shaw cells

(ren'shaw),
inhibitory interneurons that are innervated by collaterals from motoneurons and in turn form synapses with the same and adjacent motoneurons to exert inhibition; identified physiologically and by intracellular injection technique.

Renshaw,

Birdsey, 20th century U.S. neurophysiologist.
Renshaw cells - inhibitory interneurons.
References in periodicals archive ?
They showed that vibration disinhibits the recurrent inhibition of Renshaw cells. This can be attributed to segmental and suprasegmental effects on MNs or Renshaw cells.
This means that the effect of slow MNs on Renshaw cells is weak, but Renshaw cells exert a strong inhibitory effect on these MNs (26).
At lower intensities, excitement of Renshaw cells, secondary to slow MN activities, increases and these cells inhibit fast MNs in addition to slow ones.
In contrast to the low-intensity state, Renshaw cells cannot inhibit all the fast MNs, so alteration of ascending slope is more apparent in the five-point fit.
It is possible that vibration affects the cerebellum in addition to the sensory cortex and these effects inhibit Renshaw cells.
Lyshenko and his colleagues attributed vibration-induced inhibition of Renshaw cells to supraspinal centers (22).
In the RI pathway in spinal cord, it has been found that after nerve injury the Renshaw cells in adult rat appear to be inactive during reinnervation [29] and motor axon collaterals are eliminated [16, 17].
Siembab, "Principles of interneuron development learned from Renshaw cells and the motoneuron recurrent inhibitory circuit" Annals of the New York Academy of Sciences, vol.
Alvarez, "Primary afferent synapses on developing and adult Renshaw cells," Journal of Neuroscience, vol.
Rende, "Presumptive Renshaw cells contain decreased calbindin during recovery from sciatic nerve lesions," Proceedings of the National Academy of Sciences of the USA, vol.
In the spinal cord, Renshaw cell is the only interneuron in the spinal ventral horn that receives afferents directly from motoneurons and mediates recurrent inhibition back to the motoneuron themselves, through the coreleased inhibitory neurotransmitters of glycine and GABA [1-7].
In the 1940s Renshaw discovered RI of motoneuron axon collateral inhibited spinal MSR induced by activating a group of interneurons located in the spinal motoneuron area via reverse stimulation of the axon of the motoneurons [1], thus the interneuron named Renshaw cell and the inhibition named Renshaw recurrent inhibition [2, 8].