autoregulation

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autoregulation

 [aw″to-reg″u-la´shun]
control of certain phenomena by factors inherent in a situation; specifically, (1) maintenance by an organ or tissue of a constant blood flow despite changes in arterial pressure, and (2) adjustment of blood flow through an organ in accordance with its metabolic needs.
heterometric autoregulation those intrinsic mechanisms controlling the strength of ventricular contractions that depend on the length of myocardial fibers at the end of diastole.
homeometric autoregulation those intrinsic mechanisms controlling the strength of ventricular contractions that are independent of the length of myocardial fibers at the end of diastole.

au·to·reg·u·la·tion

(aw'tō-reg'yū-lā'shŭn),
1. The tendency of the blood flow to an organ or part to remain at or return to the same level despite changes in the pressure in the artery that conveys blood to it.
2. In general, any biologic system equipped with inhibitory feedback systems such that a given change tends to be largely or completely counteracted; for example, baroreceptor reflexes form a basis for autoregulation of the systemic arterial blood pressure.

autoregulation

A general term for a locally controlled feedback process—e.g., the regulation of a gene encoding a transcription factor by its own gene product.

au·to·reg·u·la·tion

(aw'tō-reg-yū-lā'shŭn)
1. The tendency of the blood flow to an organ or part to remain at or return to the same level despite changes in the pressure in the artery which conveys blood to it.
2. In general, any biologic system equipped with inhibitory feedback systems such that a given change tends to be largely or completely counteracted; e.g., baroreceptor reflexes form a basis for autoregulation of the systemic arterial blood pressure.