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A gene on chromosome 11q13 that encodes a protein that binds to NFKB1 or NFKB2 to form the NFKB complex (the most abundant form is NFKB1/RELA), which is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB); NFKBIA or NFKBIB inactivate the NFKB complex by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA or IKBKB)
marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NFKB complex.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


Carisoprodol & meprobamate
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
He is conscious, well oriented and is communicating well," read a Press Release from Dr Rela Institute and Medical Centre.
An Indian surgeon known for his expertise in liver transplants, Dr Rela has performed more than 1,200 such surgeries.
CIGB-552 Promotes the Ubiquitination of RelA Subunit of NF-[kappa]B.
However, in the first 48 hours, he responded to treatment and his vital signs stabilised though he remained critical," Dr Rela said.
Rela, who hails from India, joined Kings College Hospital London in 1991, became consultant in 11994 and has so far done over fourteen hundred liver transplants.
the RelA enzyme under amino acid starved condition, SpoT hydrolyses it (1).
suggest that RelA may present a potential therapeutic target to enhance the clinical efficacy of lapatinib in HER2-positive breast cancers.
The quality of the recording itself is worth noting: the sound is warm and rela tively close without feeling claustrophobic, and the balance between soloists and choir is perfect.
It discusses changes within the sector, and especially as they rela te to competition, globalization, cost and price pressures and mergers and allian ces between companies.
Aside from Royal Malaysia Police units, the SAR team comprises personnel from the Fire and Rescue Department, Civil Defence Force, People's Volunteer Corps (RELA) and Forestry Department, as well as Sapura and local residents.
When Professor Mohamed Rela first set eyes on Baebhen Schutkke in 1997 she was only five days old - and on the brink of death.
Caption: The Real Estate Lenders Association (RELA) announced that the association's November Breakfast at the Yale Club in New York City featured an interview and Q&A session with Gary Barnett, president and founder of Extell Development Company.