regulatory sequence

(redirected from Regulatory region)
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reg·u·la·to·ry se·quence

any DNA sequence that is responsible for the regulation of gene expression, such as promoters and operators.

regulatory sequence

[reg′yələtôr′ē]
Etymology: L, regula + sequi, to follow
a series of DNA nucleotides that regulate the expression of a gene.

reg·u·la·to·ry se·quence

(reg'yū-lă-tōr-ē sē'kwĕns)
Any DNA sequence that is responsible for the regulation of gene expression, such as promoters and operators.
References in periodicals archive ?
2009) to amplify the 5' regulatory region and exon 1 of caprine INHA gene (GenBank No.
Hypermethylation of the gene regulatory regions is documented for many cancer diseases.
Therefore, the chromatin remodeling complex which was aberrantly formed by AML1-ETO, and the hypermethylation of the CpG islands which were presented in the AML1 binding sites on the EYA4 regulatory region appeared to be the key regulatory mechanisms for the transcriptional silencing of EYA4 .
In this paper, the 5'-flanking sequence of ChMT was identified, and MRE and octamer-binding site (OBS) element-based promoter truncation analysis was performed in the upstream regulatory region of the ChMT gene.
Many neuroimaging studies consistently have indicated structural and functional deficits in prefrontal regulatory regions associated with chronic alcoholism (for review, see Buhler and Mann 2011).
Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region.
The regulatory region of the human OXTR gene displays binding sites for several transcription factors, such as growth associated binding protein, CCAAT/enhancer-binding protein (C/EBP), activator protein-1 (AP-1), Sp-1, nuclear factor-icB (NK-kB), and NF-interleukin-6 (Kimura et al.
Because deletions in the viral genome have been reported in the VP2 sequence and the regulatory region of hamster polyomavirus (11), a virus that causes lymphomas, the sequence encompassing part of the VP2 protein and the regulatory region (4,876-238) of 7 MCPyV isolates were PCR amplified with the primer set RegF/RegR (5'-TGTTCAGCTGTGAACCCAAG-3' and 5'-GAGC CTCTCTTTCTTTCCTATTT-3', respectively), cloned, and sequenced.
The first genetic construct comprises a first regulatory region operatively linked to a gene of interest and at least one repressor sequence capable of controlling the activity of the first regulatory region.
At this stage, equally parsimonious interpretations of the data presented here are that (i) there has been a compaction and simplification of upstream regulatory region DNA in the sponge lineage, and (ii) a bulk of cis-regulatory DNA is housed elsewhere in the genome.
The transgenic models we optimized here are based on the fundamental design of composite reporter gene constructs with a hormone-sensitive regulatory region upstream of a fluorescent protein cDNA.