Objective: In eukaryotes, untranslated regions located at the 3~ end (3 UTRs) of messenger RNAs (mRNAs) have been proved to be key post-transcriptional regulatory elements
controlling almost every single biological process.
The new study is one of the first to show how such regions, called regulatory elements
, can influence people's risk of disease.
His goal is to measure the three-dimensional structure to see which regulatory elements
physically touch what genes, he said.
The scientists have shown that chromosomes fold in a series of contiguous "yarns" that harbor groups of genes and regulatory elements
, bringing them in contact with each other and allowing them to work in a coordinated manner during development.
Scientists have devised a new computational model that can be used to reveal genetic regulatory elements
responsible for development of the human heart and maintenance of its function.
Note: iiBIG's 4th Annual Global Clinical Trial Partnerships: Optimizing Cross-Border Outsourcing conference - March 1 - 2, 2010, at the Hyatt in Princeton, NJ - focuses exclusively on the key legal, strategic, outsourcing, and regulatory elements
of global clinical trial partnerships.
announced today results describing predictable estrogen regulatory elements
that can be used to identify estrogenic drugs that are safer.
The identification of the repertoire of regulatory elements
in a genome is one of the major challenges in modern biology and also important for the study of gene expression and its regulatory machinery.
Battelle Memorial Institute (Richland, WA) has patented isolated gene regulatory elements
and gene transcription terminators that are differentially expressed in a native fungus exhibiting a first morphology relative to the native fungus exhibiting a second morphology.
Current legal and regulatory elements
affecting your business," will be addressed by Eric Greenberg, principal, Eric F.
This, in turn, could lead to the identification of genetic contributors to human illnesses and the discovery of key regulatory elements
in the human genome.
Sifting through the latter, so-called junk, DNA for the genes and regulatory elements
has been a formidable challenge.