sibutramine

(redirected from Reductil)
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Related to Reductil: phentermine, sibutramine, Xenical

sibutramine

 [si-bu´trah-mēn″]
an appetite suppressant used as the hydrochloride salt in treatment of obesity; administered orally.

sibutramine

(sə-byo͞o′trə-mĭn, -mēn′)
n.
A drug formerly used in the management of obesity, withdrawn from the US market in 2010 because of its association with an increased risk of heart attacks and strokes.

sibutramine

A central, appetite-suppressing agent that blocks reuptake of serotonin, norepinephrine and, to a lesser extent, dopamine; it provides a sensation of fullness from lesser amounts of food, and increases metabolism. Sibutramine was approved for use as a dietary adjunct in the mid-1990s and was heavily marketed until 2010, when it was withdrawn from the market due to the increased risk of cardiovascular events and strokes associated with its use. Sibutramine is a Schedule-IV Controlled Substance.

 
Indications
Obese patients with an initial BMI of ≥ 30 kg/m2 or ≥ 27 kg/m2 in addition to other factors (e.g., hypertension, diabetes, dyslipidemia).

Adverse effects
Headache, dry mouth, anorexia, constipation.

Contraindications
Concurrent MAOIs, other central appetite suppressants, anorexia nervosa.

sibutramine

Meridia® Obesity A central, appetite-suppressing agent that blocks reuptake of serotonin and norepinephrine, and, to a lesser extent dopamine; it provides a sensation of fullness from less food, and ↑ metabolism Indications Obese Pts with an initial BMI of ≥ 30 kg/m2 or ≥ 27 kg/m2 with other factors–eg, HTN, DM, dyslipidemia Cons Sibutramine is a Schedule IV Controlled Substance Adverse effects Headache, dry mouth, anorexia, constipation Contraindications Concurrent MAOIs, other central appetite suppressants, anorexia nervosa. See Obesity.

si·bu·tra·mine

(si-byū'tră-mēn)
A serotonin and noradrenaline reuptake inhibitor used to reduce appetite to encourage weight loss.

sibutramine

An antiobesity drug that acts on the nervous system in a manner similar to that of Prozac so that the patient is able to feel satisfied with smaller amounts of food. The drug is not recommended for people under 18 and is used for a maximum period of one year. It is prescribed mainly for those with a body mass index (BMI) of 30 or over. Brand name Reductil.

Sibutramine

An appetite-suppressing drug that may increase the activity of norepinephrine and serotonin in the brain.
Mentioned in: Weight Loss Drugs

si·bu·tra·mine

(si-byū'tră-mēn)
A serotonin and noradrenaline reuptake inhibitor used to reduce appetite to encourage weight loss.
References in periodicals archive ?
"Reductil", which was approved by FDA in 1997, is only provided according
Shock jock Gerry admitted taking the banned slimming tablet Reductil throughout 2007 but it is not clear if he was still taking the pills when he collapsed and died.
The product was a clear winner, with Reductil scoring an average 4.18 out of 5 stars, ahead of second rated SLIMist, with an average 4.15 rating and in third place, Celebrity Slim at 4.13 stars.
BAHRAIN has banned the sale of weight loss and anti-obesity drug Reductil and ordered it be immediately withdrawn from all pharmacies.
Abbott manufactures sibutramine under the brand names Reductil, Meridia, Sibutral, Ectiva and Raductil.
The Medicines and Healthcare Products Regulatory Agency has told doctors to stop prescribing sibutramine, marketed as Reductil, and review its use in patients already taking it.
"Ongoing litigation poses a significant challenge to two of Abbott's most important growth driver franchises, Humira and TriCor, while Abbott's exposure to generic competition is gathering pace with patent expiries to Depakote, Biaxin, Synthroid, as well as its lucrative stealth products such as Zemplar and Reductil," explains Joshua Owide, pharmaceutical markets senior analyst at Datamonitor.
The study looked at the use of orlistat (Xenical), sibutramine (Reductil) and rimonabant (Acomplia) in children up to 18 from January 1999 to December 2006.
Sibutramine, marketed as Reductil, is an appetite suppressant while tadalafil, commonly known as Cialis, treats erectile dysfunction in a similar way to Viagra.
70% of the Obesity Task Force's funding comes from the two drug companies that make 'the popular weight-loss pills Xenical, Meridia, and Reductil.
The pills are mainly plant based and totally different from prescription drugs such as Reductil and Xenical, which are only given to people who are clinically obese.