Grepafloxacin, see there.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
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In 1999, the FDA and manufacturers withdrew one antibiotic, Raxar, from the market and greatly curtailed the use of another, Trovan, because of harmful side effects.
For the recalled antibiotic Raxar, the best information that I can find indicates that it was associated with 13 deaths from heart arrhythmia.
I do not have sufficient data to analyze the decision to withdraw Raxar and Trovan, and so I will not address that issue.
The eight drugs lately withdrawn were GlaxoSmithKline's Lotronex, for irritable bowel syndrome; American Home Products' Redux, a diet aid; the Bayer Corporation's Raxar, an antibiotic; Pfizer's Trovan, also an antibiotic; Roche's Posicor, a blood-pressure medication; Wyeth-Ayerst's Duract, a painkiller; Warner-Lambert's Rezulin, a diabetes drug; and, this spring, Organon's Raplon, an anesthetic.
Grepafloxacin, which was marketed as Raxar, was approved in 1997 for the treatment of community-acquired pneumonia, acute bacterial exacerbations of chronic bronchitis, uncomplicated gonorrhea, and nongonococcal urethritis and cervicitis.
The drug, Raxar, is used to treat illnesses including pneumonia, bronchitis and some sexually transmitted infections.
$79.80 (10 days) (Cipro) sparfloxacin 400 mg day 1 $73.48 (10 days) (Zagam) followed by 200 mg/day for 9 days grepafloxacin Not applicable Not applicable (Raxar) PENICILLIN amoxicillin 500 mg t.i.d.
New drugs such as Zyban - essentially an antidepressant repackaged and repatented as a smoking cessation aid - and respiratory anti-infective Raxar, are expected to provide further sales growth.
$79.80 (10 days) (Cipro) grepafloxacin 600 mg once a $61.80 (10 days) (Raxar) day sparfloxacin 400 mg day 1 $73.48 (10 days) (Zagam) followed by 200 mg/day for 9 days PENICILLIN amoxicillin 500 mg t.i.d.