Rathke cleft cyst

Rath·ke cleft cyst

(raht'kĕ),
an intrasellar or suprasellar cyst lined by cuboidal epithelium derived from remnants of Rathke pouch.

Rath·ke cleft cyst

(raht'kĕ kleft sist)
An intrasellar or suprasellar cyst lined by cuboidal epithelium derived from remnants of the Rathke pouch.

Rathke,

Martin H., German anatomist, physiologist, and pathologist, 1793-1860.
Rathke bundles - muscular bundles on the lining walls of the ventricles of the heart. Synonym(s): trabeculae carneae
Rathke cleft cyst - an intrasellar or suprasellar cyst lined by cuboidal epithelium derived from remnants of Rathke pouch. Synonym(s): Rathke cyst
Rathke column
Rathke cyst - Synonym(s): Rathke cleft cyst
Rathke diverticulum - a tubular outgrowth of ectoderm from the stomodeum of the embryo. Synonym(s): pituitary diverticulum; Rathke pocket; Rathke pouch
Rathke duct
Rathke fold - two fetal folds of mesoderm.
Rathke pocket - Synonym(s): Rathke diverticulum
Rathke pouch - Synonym(s): Rathke diverticulum
Rathke pouch tumor - a suprasellar neoplasm, usually cystic, that develops from the nests of epithelium derived from Rathke pouch. Synonym(s): craniopharyngioma
Rathke punch
References in periodicals archive ?
Normal posterior gland may be included as a small fragment in what is otherwise obviously a pituitary adenoma or some other sellar region mass (Figure 3, f), or may be the majority of a small biopsy sample, especially if the neurosurgeon is resecting a cystic lesion that occurs at the junction between anterior and posterior pituitary gland, that is, a Rathke cleft cyst.
Finally, synaptophysin IHC positivity in a finely fibrillar pattern highlights small fragments of posterior gland that can also be included, especially in specimens being assessed for Rathke cleft cyst.
Nevertheless, the most frequent cyst in the sellar region is Rathke cleft cyst (RCC).
Rathke cleft cyst epithelium was originally thought to have a distinctive cytokeratin profile with strong cytokeratin 7 immunopositivity and cytokeratin 20 immunonegativity that allowed easy distinction from cystic craniopharyngioma, (26) but this has now been recognized to have a far more variable keratin profile.
Differential expression of cytokeratins 8 and 20 distinguishes craniopharyngioma from Rathke cleft cyst.
e, The finding of dense amorphous mucin from a pituitary region mass is virtually pathognomonic of Rathke cleft cyst, although technicallysome consideration might be given to a cystic teratoma; the latter is exceedingly rare in this site.
The overwhelming majority of sellar region masses are pituitary adenomas (85%), followed by craniopharyngiomas (3%), Rathke cleft cysts (2%), meningiomas (1%), and metastases (0.
Tumors of the Sellar region: (a) Pituitary adenoma (b) Craniopharyngioma (c) Rathke cleft cyst.
The differential diagnoses to consider include a non-haemorrhagic pituitary macro-adenoma, a craniopharyngioma, a Rathke cleft cyst, a pituitary abscess, primary intra-pituitary haemorrhage, or a giant thrombosed intra-sellar aneurysm.
Pituitary adenoma, craniopharyngioma, and Rathke cleft cyst involving both intrasellar and suprasellar regions: Differentiation using MRI.