rate-determining step

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rate-determining step

The chemical reaction in a series of sequential reactions that takes the longest to occur.
See also: step
References in periodicals archive ?
The enzyme 1-deoxy-D-xylulose-5-phosphate synthase (DXS) catalyses the first and rate-limiting step of the MEP pathway and it is also involved in microbial vitamin B1 and vitamin B6 biosynthesis, making it an interesting target in microbes.
In addition, VFA degradation is the rate-limiting step in anaerobic wastewater treatment because it is subject to the acetic acid degradation pathway and can decelerate and decrease acetic acid conversion [10, 11].
Value of the intercept suggest role of surface adsorption in rate-limiting step [30].
Cytochrome P450 side-chain cleavage enzyme (CYP11A1) is the first enzyme and catalyzes the rate-limiting step of steroidogenesis.
Therefore, the interfacial reaction constituted the rate-limiting step of the process.
t0.5) is straight line passing from origin, then intra-particle diffusion becomes rate-limiting step. The adsorption data indicated that removal of dye from aqueous phase is a complex process, involving both boundary layer diffusion as well as intra-particle diffusion [17].
Processing, rather than meltdown, became the new rate-limiting step for melting.
Paragangliomas located in the skull base, head and neck, and thyroid are associated with the parasympathetic nervous system, which often lacks tyrosine hydroxylase (the rate-limiting step in dopamine synthesis).
The kind of rate-limiting step of the procedure is the calvarium, the head is basically the biggest part.
I say this because, to a good first approximation, I don't think that medicinal chemistry is the rate-limiting step in the whole process, or the one most in need of fixing.
Andrew Hessel: The rate-limiting step for biotechnology is manual work at the lab bench and software tools that accurately connect to bench research.
The rate of the drug release is dependent solely on the rate-limiting step of the intraconversion process.

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