rate-determining step

(redirected from Rate limiting step)
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rate-determining step

The chemical reaction in a series of sequential reactions that takes the longest to occur.
See also: step
References in periodicals archive ?
Burggraaf, "Importance of the surface exchange kinetics as rate limiting step in oxygen permeation through mixed-conducting oxides," Solid State Ionics, vol.
The rate limiting step is the evaporation of the cosolvent from the surface of the film.
The supply of initiator and monomer is regulated by the isoprenoid pathway (figure 2), with hydroxyl-methyl-glutaryl co-enzyme A reductase (HMGR) often being a rate limiting step. In all three species, polymerization rate is affected by both the concentration and size of the initiator and by the concentration of the monomer (ref.
Because the association studies of unrelated patients require thousands of research subjects and controls to differentiate between genetic and environmental affects, DNA and tissue samples have emerged as a rate limiting step. Physicians can play an important role in encouraging their patients to take part in such research and in requiring that the research be conducted ethically and with sensitivity toward the research subjects.