chelation

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che·la·tion

(kē-lā'shŭn),
Complex formation involving a metal ion and two or more polar groupings of a single molecule; in heme, the Fe2+ ion is chelated by the porphyrin ring. Chelation can be used to remove an ion from participation in biologic reactions, as in the chelation of Ca2+ of blood by EDTA, which thus acts as an anticoagulant.
[G. chēlē, claw]
Farlex Partner Medical Dictionary © Farlex 2012

che·la·tion

(kē-lā'shŭn)
Complex formation involving a metal ion and two or more polar groupings of a single molecule; can be used to remove an ion from participation in biologic reactions, as in the chelation of Ca2+ of blood by ethylenediaminetetraacetic acid, which thus acts as an anticoagulant in vitro.
[G. chēlē, claw]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

chelation

the binding of a metal ion to an organic molecule from which it can later be released. In complex molecules, chelation results in, for example, zinc binding with amino acids in carboxypeptidase enzymes. Some chelating agents, such as penicillamine, are drugs used to treat metal poisoning: the metal is bound to the drug and can then be excreted safely Chelation also enables plants to take up metal ions such as iron that are not readily available in a free state.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

Chelation

The process by which a molecule encircles and binds to a metal and removes it from tissue.
Mentioned in: Heavy Metal Poisoning
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.

che·la·tion

(kē-lā'shŭn)
Complex formation involving a metal ion and two or more polar groupings of a single molecule.
[G. chēlē, claw]
Medical Dictionary for the Dental Professions © Farlex 2012