On mammography, a spiculated de novo lesion that was denser than the radiographically dense
breast parenchyma was identified on right upper breast (Figure 2a).
Screening mammography sensitivity for cancer detection ranges from 83% --95% and drops down to nearly half (30%-48%) in patients with radiographically dense
and glandular breast.
Breast cancer detection using automated whole breast ultrasound and mammography in radiographically dense
It's been a decade since the pivotal DMIST study determined that digital mammography delivers greater breast cancer detection accuracy than film-screen mammography in women under age 50 and those with radiographically dense
Although this has shown no significant difference in diagnostic accuracy between FFDM and SFM , the DMIST did show that digital mammography is more accurate in women under the age of 50 years, women with radiographically dense
breasts, and premenopausal and perimenopausal women [15,16].
While fat appears dark on a mammogram, other areas of the breast are radiographically dense
and look light, which is referred to as mammographic density.
(1) Radiographically dense
breasts also can present a diagnostic imaging challenge for the early detection of breast carcinoma because of the following factors (2):
A lot of "structured noise" is created by the overlap of normal radiographically dense
The overlap of normal radiographically dense
structures can obscure existing neoplastic tissue and also can create the illusion of a lesion where no true lesion is present.
Mammograms in women with radiographically dense
breasts are more difficult to interpret, and may not reveal a cancer that is present.
Breast cancer detection: using automated whole breast ultrasound and mammography in radiographically dense