racemic

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Related to Racemic mixture: chirality, racemic epinephrine, Diastereomers

racemic

[ra-se´mik]

optically inactive, being composed of equal amounts of dextrorotatory and levorotatory isomers.

ra·ce·mic (r),

(rā-sē'mik, -sem'ik),

Denoting a mixture of optically active compounds that is itself optically inactive, being composed of an equal number of dextro- and levorotatory substances, which are separable. Those compounds chracterized by two or more chiral centers and internal compensation (for example, an internal line of symmetry), and are therefore not separable into d or l (or + and -) forms, receive the prefix meso-) (for example, meso-cystine).

Farlex Partner Medical Dictionary © Farlex 2012

ra·ce·mic

(rā-sē'mik)

Denoting a mixture of optically active compounds that is itself optically inactive, being composed of an equal number of dextrorotatory and levorotatory substances, which are separable.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

ra·ce·mic

(rā-sē'mik)

Denoting mixture of compounds that is itself optically inactive, being composed of an equal number of dextrorotatory and levorotatory substances.

Medical Dictionary for the Dental Professions © Farlex 2012

References in periodicals archive ?

On the other hand, many pyrethroids are marketed as racemic mixtures, which have in equal enantiomeric proportions.

Pyrethroid Stereoisomerism: Diastereomeric and Enantiomeric Selectivity in Environmental Matrices--A Review

In this study, chiral separation of 36 racemic mixtures of synthetic cathinone derivatives was carried out: fourteen of them were selected in the spiked mixtures, and each enantiomer was quantitated in urine and plasma as shown in the example of nor-mephedrone in Figure 1.

Simultaneous Quantitative Determination of Synthetic Cathinone Enantiomers in Urine and Plasma Using GC-NCI-MS

Apotex, Inc., (80) the court found that the patented dextrorotatory isomer (81) was not obvious in light of the known racemic mixture. (82) Racemates of two other thienopyridines had been resolved, and there was no observed advantage to separation in either case.

Expecting the unexpected

(124) This receptorsubstrate affinity is responsible for the physiological differences observed between enantiomers and is one reason why pharmaceutical drugs are often administered as a single enantiomer rather than as a racemic mixture. (125)

Deuterated drugs: unexpectedly nonobvious?

Due to non-availability, the racemic mixture was not included in the experiment.

Chemical analysis of female volatiles and field response of the coffee leafminer moth (lepidoptera: lyonetiidae) to stereoisomers of its major sex pheromone component

This indicates that the % ee of the racemic mixture varies constantly.

The effects of temperature on the specific rotation of isoborneoland (S)-(-)-endo borneolat a specific concentration - part II

Twenty-one of these compounds were isolated, tested, and included in the specification of the genus patent; one of these compounds was the racemic mixture of clopidogrel.

A shift in the Canadian law of obviousness: a comment on Sanofi-Synthelabo Canada Inc. v. Apotex Inc

Table 1 Clinical studies of stimulant use in patients with bipolar disorder Stimulant(s) studied Study design Patients studied Traditional stimulants Adjunctive methylphenidate Chart review, 16 adults (5 with naturalistic (12) comorbid ADHD, 11 with bipolar depression) Adjunctive methylphenidate Chart review of 8 adults (BD II) or racemic mixture of AMPH sedation and salts depressive symptoms (13) Adjunctive methylphenidate 12-week open study, 12 adults (10 BDI.

Stimulants for adult bipolar disorder? Adding a stimulant could improve residual symptoms, but it also might cause serious side effects, toxicities, and destabilization

Methadone, a synthetic opioid that is available in the United States as a racemic mixture of two isomers, has several advantages over other opioid analgesics.

Managing pain with Methadone can be complex

Ofloxacin otic contains a lesser amount of active antibiotic because the racemic mixture of ofloxacin contains only 1,500 [micro]g/ml of the active levo isomer; therefore organisms might be considered to be potentially resistant if the MIC is 128 [micro]g/ml.

Bacterial resistance to quinolone otic drops is nearly zero

Warfarin is a racemic mixture of two enantiomers that are metabolised by different inducible isoforms of the cytochrome P450 family.

Haematuria in HIV--an interactive web

A racemic mixture is a preparation containing 50% L-thyroxine and 50% D-thyroxine.

The history of iodine in medicine Part II: the search for and the discovery of thyroid hormones

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