(RNA interference) is a natural cellular process of gene silencing that represents one of the most promising and rapidly advancing frontiers in biology and drug development today.
Because of its ability to silence any gene once the sequence is known, RNAi
has been adopted as the research tool to discriminate gene function.
melanogaster that the proteins Dic1, Loq and Ago1 are involved in the miRNA pathway whereas Dic2, R2d2 and Ago2 are involved in the RNAi
pathway (Mukherjee and Hanley, 2010).
These lipid researchers continue to develop novel lipids specifically for the purpose of RNAi
When we disrupt the expression of it with RNAi
, we observe multiple effects in immature stages as well as in adults," Vander Meer says.
Researchers used RNAi
to screen human cells to identify genes that help parkin tag damaged mitochondria.
Tekmira continues to build upon its leadership position and invest in its RNAi
technologies by making advancements in LNP potency, tolerability, biodistribution, targeting, process development, and manufacturing, as well as the evaluation of new RNAi
Silence Therapeutics is a leading RNAi
therapeutics product and technology platform company with proprietary delivery systems.
The journal Nature Biotechnology reported earlier this year that efforts to develop new drugs based on RNAi
Benitec Limited (ASX:BLT) (PINK:BNIKF) holds a dominant position in expressed RNA interference (RNAi
)-based human therapeutics, with a transformational platform technology supported by a robust and extensive intellectual property portfolio.
Therapeutic applications of RNAi
; methods and protocols.