polymerase

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Related to RNA-dependent RNA polymerase: replicase

polymerase

 [pah-lim´er-ās]
an enzyme that catalyzes polymerization.
polymerase chain reaction a rapid technique for in vitro amplification of specific DNA or RNA sequences, allowing small quantities of short sequences to be analyzed without cloning.

pol·ym·er·ase

(pol-im'ĕr-ās),
General term for any enzyme catalyzing a polymerization, as of nucleotides to polynucleotides, thus belonging to EC class 2, the transferases.

polymerase

/po·lym·er·ase/ (pah-lim´er-ās) an enzyme that catalyzes polymerization.

polymerase

(pə-lĭm′ə-rās′, -rāz′, pŏl′ə-mə-)
n.
Any of various enzymes, such as DNA polymerase, RNA polymerase, or reverse transcriptase, that catalyze the formation of polynucleotides of DNA or RNA using an existing strand of DNA or RNA as a template.

polymerase

[pə·lim′ər·ās]
any enzyme that catalyzes polymerization, especially of nucleotides to polynucleotides.

POLA1

A gene on chromosome Xp22.1-p21.3 that encodes the catalytic subunit of DNA polymerase that plays a key role in initiating DNA replication.

pol·ym·er·ase

(pŏ-lim'ĕr-ās)
General term for any enzyme catalyzing a polymerization, as of nucleotides to polynucleotides, thus belonging to EC class 2, the transferases.

polymerase

Any enzyme that promotes the linkage of a number of similar or identical chemical subunits into repetitive long-chain molecules (polymers), especially of NUCLEOTIDES to form DNA or RNA. Derivation as in POLYMER with the -ase suffix denoting an enzyme.

polymerase

an enzyme that catalyses the joining of DNA or RNA nucleotides.

polymerase

an enzyme that catalyzes polymerization, particularly of nucleic acids.

polymerase chain reaction
see pcr1.
RNA polymerase
1. an enzyme that synthesizes an RNA copy of the sequence in a limited region of DNA in a process known as DNA transcription. Called also DNA-dependent RNA polymerase.
2. a viral enzyme that synthesizes RNA from an RNA template during viral replication. Called also RNA-dependent RNA polymerase.
RNA-dependent RNA polymerase
see RNA polymerase (above).
Taq polymerase
a DNA polymerase that functions at high temperature; derived from the bacterium Thermus aquaticus and used in the polymerase chain reaction.
References in periodicals archive ?
To determine whether picobirnaviruses could also be present in the human respiratory tract, we performed a diagnostic genogroup I picobirnavirus PCR, with degenerated primers, that targeted the RNA-dependent RNA polymerase coding region (1,4,8) on 309 bronchoalveolar lavage specimens collected from 309 patients with respiratory disease of unknown origin in the Netherlands during 2003-2006.
The aim of the study was to detect porcine calicivirus (norovirus and sapovirus) in domestic pigs by using reverse transcription--PCR (RT-PCR), using the generic primer pairs p289/p290 designed for the calicivirus RNA-dependent RNA polymerase gene (319 nt for norovirus or 331 nt for sapovirus) (8).
The virus genome consists of 3 segments of negative-stranded RNA; the large (L) segment encodes viral RNA-dependent RNA polymerase, the medium (M) segment encodes glycoprotein precursor, and the small (S) segment encodes nucleocapsid protein.
The first ORF (ORF1) encodes a polypeptide with regions of similarity to helicase, cysteine proteinase, and RNA-dependent RNA polymerase (RdRp)-encoding regions of picornaviruses (5).
We analyzed these samples for noroviruses in 2003 by using JV12Y and JV13I, a recently optimized primer set that allows detection of a broad range of noroviruses by targeting the RNA-dependent RNA polymerase (9).
Norovirus ORF1 encodes nonstructural proteins, including the RNA-dependent RNA polymerase, ORF2 encodes the capsid protein, and ORF3 encodes a small capsid protein (1).
The polyproteins are autocatalytically processed into replicative enzymes, including the RNA-dependent RNA polymerase, which synthesizes both negative-sense and positive-sense sgRNAs, and the positive-sense sgRNAs serve as mRNAs for all of the open reading frames (ORFs) downstream of ORF1b (6,11).