RNA splicing


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splic·ing

(splīs'ing),
1. Attachment of one DNA molecule to another. Synonym(s): gene splicing
2. Removal of introns from mRNA precursors and the reattachment or annealing of exons. Synonym(s): RNA splicing
3. Posttranslational modification of a protein involving two proteolytic enzymes and one ligation; results in the removal of an internal sequence of amino acyl residues.

splic·ing

(splīs'ing)
1. Attachment of one DNA molecule to another.
Synonym(s): gene splicing.
2. Removal of introns from mRNA precursors and the reattachment or annealing of exons.
Synonym(s): RNA splicing.

splic·ing

(splīs'ing)
1. Attachment of one DNA molecule to another.
Synonym(s): gene splicing.
2. Removal of introns from mRNA precursors and the reattachment or annealing of exons.
Synonym(s): RNA splicing.
References in periodicals archive ?
Under the terms of the multi-year agreement, H3 and Bristol-Myers Squibb will jointly conduct the research focused on developing immune therapies using H3's RNA splicing platform.
Working with cultures of human lung cells, the team's proposed mechanism of how flu A virus interacts with human RNA splicing machinery suggests that keeping human splicing proteins from binding to the viral genomewould help to stop its replication.
Likewise, we observed different effects of U2af1 knockdown on iCM generation from that on iPSC reprogramming [31], suggesting distinct RNA splicing regulation between iCM and iPSC reprogramming processes.
RNA splicing results in the formation of mature mRNA transcripts derived from exons, the protein coding portion of the genome.
Gene function enrichment analysis of 12 overlapping DEGs (between control versus COPD and COPD versus BYF groups) indicates that BYF treatment can reduce translation and RNA splicing in COPD.
An intron is any nucleotide sequence within a gene that is removed by RNA splicing to generate the final mature RNA product of a gene.
Digoxin can cut and paste the HERV RNA by modulating RNA splicing generating RNA viroidal diversity [18].
Guthrie, an American Cancer Society research professor of molecular genetics, pioneered the use of budding yeast as a model organism for a mechanistic understanding of messenger RNA splicing.
Often, testing the effect of UVs on RNA splicing becomes essential to assess their pathogenicity.
Mechanisms such as RNA splicing, RNA processing, polyadenylation, and the action of regulatory proteins occur at the transcriptional level.
Sharp, who was later honored for his work with split genes and RNA splicing.
Introns are initially transcribed when the initial messenger RNA (mRNA) is synthesized but are subsequently removed by a process called RNA splicing prior to nuclear transport of the maturemRNAto the cytoplasm for translation.