RNA splicing

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Related to RNA splicing: alternative RNA splicing, Alternative splicing

splic·ing

(splīs'ing),

1. Attachment of one DNA molecule to another. Synonym(s): gene splicing

2. Removal of introns from mRNA precursors and the reattachment or annealing of exons. Synonym(s): RNA splicing

3. Posttranslational modification of a protein involving two proteolytic enzymes and one ligation; results in the removal of an internal sequence of amino acyl residues.

Farlex Partner Medical Dictionary © Farlex 2012

splic·ing

(splīs'ing)

1. Attachment of one DNA molecule to another.
Synonym(s): gene splicing.

2. Removal of introns from mRNA precursors and the reattachment or annealing of exons.
Synonym(s): RNA splicing.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

splic·ing

(splīs'ing)

1. Attachment of one DNA molecule to another.
Synonym(s): gene splicing.

2. Removal of introns from mRNA precursors and the reattachment or annealing of exons.
Synonym(s): RNA splicing.

Medical Dictionary for the Dental Professions © Farlex 2012

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References in periodicals archive ?

Under the terms of the multi-year agreement, H3 and Bristol-Myers Squibb will jointly conduct the research focused on developing immune therapies using H3's RNA splicing platform.

Eisai: Bristol-Myers Squibb and H3 Biomedicine Announce Research Collaboration to Advance Novel Therapeutics Leveraging H3's RNA Splicing Platform

Working with cultures of human lung cells, the team's proposed mechanism of how flu A virus interacts with human RNA splicing machinery suggests that keeping human splicing proteins from binding to the viral genomewould help to stop its replication.

Study Reveals New Therapeutic Target for Slowing Spread of Flu Virus

Likewise, we observed different effects of U2af1 knockdown on iCM generation from that on iPSC reprogramming [31], suggesting distinct RNA splicing regulation between iCM and iPSC reprogramming processes.

A Loss of Function Screen of Epigenetic Modifiers and Splicing Factors during Early Stage of Cardiac Reprogramming

RNA splicing results in the formation of mature mRNA transcripts derived from exons, the protein coding portion of the genome.

Molecular Genetic Biomarkers in Myeloid Malignancies

Gene function enrichment analysis of 12 overlapping DEGs (between control versus COPD and COPD versus BYF groups) indicates that BYF treatment can reduce translation and RNA splicing in COPD.

Effects and mechanism of Bufei Yishen Formula in a rat chronic obstructive pulmonary disease model

An intron is any nucleotide sequence within a gene that is removed by RNA splicing to generate the final mature RNA product of a gene.

Increasing splicing site prediction by training gene set based on species

Digoxin can cut and paste the HERV RNA by modulating RNA splicing generating RNA viroidal diversity [18].

Endosymbiontic actinidic archaeal synthesis of digoxin from cholesterol regulates cellular function and contributes to disease pathology

Guthrie, an American Cancer Society research professor of molecular genetics, pioneered the use of budding yeast as a model organism for a mechanistic understanding of messenger RNA splicing.

American Society for Biochemistry and Molecular Biology Honors 11 Outstanding Scientists

Often, testing the effect of UVs on RNA splicing becomes essential to assess their pathogenicity.

Alternative splicing and molecular characterization of splice site variants: BRCA1 c.591C>T as a case study

Mechanisms such as RNA splicing, RNA processing, polyadenylation, and the action of regulatory proteins occur at the transcriptional level.

Introduction to proteomics

Sharp, who was later honored for his work with split genes and RNA splicing.

2 leading gene experts hired; `UMass ... really coming into its own'

Introns are initially transcribed when the initial messenger RNA (mRNA) is synthesized but are subsequently removed by a process called RNA splicing prior to nuclear transport of the maturemRNAto the cytoplasm for translation.