RNA processing

processes involved in the formation of mature, fully functional RNA species from primary RNA transcripts. For eukaryotic mRNA this may involve the removal of INTRONS (RNA splicing) and the addition of a cap at the 5′-end (See CAPPING (1)) and of a Poly(A) tail (see POLYADENYLATION). Generally little modification is made to prokaryotic mRNA; rRNA and tRNA in PROKARYOTES and EUKARYOTES are both modified. Both are cut out of large primary transcripts. For tRNA some of the bases are modified chemically. These processes occurring after TRANSCRIPTION are also called POSTTRANSCRIPTIONAL MODIFICATIONS.

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Our preliminary data reveals that a potent structure in gene expression, The mrna cap, Which co-ordinates rna processing and translation initiation, Is crucial for the development and activation of cd8 t cells.

Tcaps: Mrna cap regulation and function in cd8 t cells

TDRD4/ring finger protein 17 (RNF17) and TDRD5 are mainly expressed in chromatoid bodies and involved in RNA processing for spermatogenesis (Smith et al.

Tudor domain containing protein TDRD12 expresses at the acrosome of spermatids in mouse testis

Their topics include: to the cell and beyond, the realm of molecular genetics, nucleic acids, principles and applications of recombinant DNA, the physical structure of the genomic material, transcription in eukaryotes, the regulation of transcription in bacteria, RNA processing, the players and process of translation, protein processing and modification, DNA replication in bacteria and eukaryotes, and DNA repair.

Molecular Biology: Structure and Dynamics of Genomes and Proteomes

The team defined the meaning of "words" in RNA, allowing identification of patterns in RNA molecules that proteins use to control RNA processing and movement, which are often altered in disease.

New therapy for autism being explored after RNA code gets cracked

Reduced RNA processing inhibited the translation of proteins required to maintain the mitochondrial electron transport chain that consumes oxygen during cell respiration to produce energy.

Correcting Human Mitochondrial Mutations

Nuclear biologists describe the dynamic remodeling of the nuclear envelope during the cell cycle, the positioning of genes relative to functional landmarks, the Cajal body and histone locus body, DNA damage response, RNA processing, and nuclear ataxias.

The nucleus

There is growing evidence that abnormalities in RNA processing might play a central role in the degeneration of motorneurons.

Bunina bodies

Congenital neutropenia due to defective RNA processing

New insights into the genetics of congenital neutropenia/Konjenital notropenilere genetik bakys

This polypeptide, CHAMP (cardiac helicase activated by MEF2 protein), bears striking resemblance to a number of other helicase proteins and appears to play a role in RNA processing and transcriptional control in heart muscle.

University of Texas obtains United States patent

Most of these motifs are shared among many loci, suggesting that genomes are assembled like Lego blocks from a repertoire of more basic sequence elements, many of which do not encode proteins but other important functions such as transcription, translation, RNA processing, DNA replication, and chromatin condensation.

Origin of genetic information and evolution of biological species

Finally, antipolymyositis/Scl (anti-PM Scl) and anti-Th/To (which recognizes certain RNA processing enzymes) anti-bodies are seen in about 2% of scleroderma patients.

Abnormal capilloscopy key in Raynaud's patients: examine the periungual area of the finger under gel with an ophthalmoscope to predict scleroderma

The only false-positive case was presumably attributable to contamination during RNA processing.