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Treating RMSF early with the proper antibiotic, doxycycline, is the best way to prevent severe illness or a fatal outcome in patients of all ages.
More than 300 cases of RMSF and 20 deaths have occurred on Arizona Indian reservations between 2002 and 2014, illustrating the severity of the epidemic.
Prevention is the same as that described for Lyme disease and RMSF.
More than 13,500 cases of RMSF and related infections were reported in the United States between 2008 and 2012.
Similarly to the circumstances in the Sao Paulo metropolitan area, most of the RMSF cases in the eastern United States have occurred in children and women (32,33), and infections in canines have been associated repeatedly with an increased risk for disease in owners (34).
may be contributing to the increase in seroepidemiologic surveillance trends reported for RMSF.
This sixth statement is supported by the fact that Itu municipality is an area where RMSF laboratory-confirmed cases in humans have been reported since 2003 (www.
In comparison, RMSF was described as a very severe disease with a mortality rate of 65%-90% in western Montana (23).
rickettsii was isolated from 2 of the patients who died and from a pool of Amblyomma cajennense ticks from the Ollas Arriba area, findings that suggest that this tick is a vector of RMSF in Panama (2).
RMSF in Colombia is seldom considered in the differential diagnosis for febrile disease; possible causes include the lack of an adequate diagnostic infrastructure and the invisibility of tick- and fleaborne infectious diseases in most medical curricula.
parkeri rickettsiosis have been described only twice (1,8), and the prevalence of this disease is unknown; however, many cases of this infection have likely been misidentified as RMSF (6).
We report a case of fatal RMSF in a previously healthy child in southwestern Mexico, where this infection had not previously been recognized.
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