TAP2

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TAP2

A gene on chromosome 6p21.3 that encodes a member of the MDR/TAP subfamily of the superfamily of ATP-binding cassette (ABC) transporters, which plays a role in multidrug resistance and antigen presentation. TAP2 forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum.

Molecular pathology
TAP2 mutations have been tentatively linked to ankylosing spondylitis, type-1 diabetes and coeliac disease.
References in periodicals archive ?
In these studies it was proved that PEEK cages are secure biomaterial for intermediate ring11 and the flexibility is similar with bones.12 We also used PEEK cage in the study.
Industrial Research Ring11. Pleasure Craft Insurance.