RAD18(redirected from RING finger protein 73)
RAD18A gene on chromosome 3p25-p24 that is highly similar to the Saccharomyces cerevisiae DNA damage repair protein Rad18; it interacts with the human homologue of the yeast Rad6 protein via a conserved RING finger motif.
Mutation of the RING finger motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.