Now a second manufacturer has produced what would appear to be a comparable index, the so-called RET-Y (5, 6) generated by the Sysmex XE-2100 analyzer.
Specimens were collected for complete blood cell count, CHr, Ret-Y, sTfR, ferritin, and CRP within 24 h of admission.
Ret-Y is the mean value of the forward-scattered-light histogram of the reticulocyte population, currently expressed in arbitrary units (AU).
The regression formula (function y = [5.5569e.sup.0.001x)] might also be used to transform the arbitrary channel numbers of the RBC-Y and RET-Y into their respective hemoglobin equivalents, expressed as picograms and denoted as RBC-[H.sub.e] and RET-[H.sub.e], respectively.
Method comparison between CHr and Ret-Y demonstrated a curvilinear relationship as shown in Fig.
Comparison between CHr and Ret-Y showed that a Ret-Y value <1630 AU corresponded to a CHr <28 pg.
The diagnostic plot combines the CHr or the Ret-Y with the sTfR-F index to assess the relationship between iron supply for erythropoiesis (sTfR-F index) and FID (CHr and Ret-Y).
The final study involved assessment of the selectivity of the Ret-Y compared with that of CHr in disease-specific anemias.
In conclusion, the reticulocyte channel of the Sysmex XE-2100 series offers a new reticulocyte index, the Ret-Y, which shows good correlation with the CHr.
The new reticulocyte parameter (RET-Y) of the Sysmex XE 2100.