REAL classification

REAL classification

a classification of lymphoma first published in 1994 and based on the correlation of clinical features of lymphomas with their histopathology and immunophenotype and genotype of neoplastic cells; groups lymphoproliferative diseases into chronic leukemia/lymphoma, nodal or extranodal lymphoma, acute leukemia lymphoma, plasma cell disorders, and Hodgkin disease.
[Revised European-American lymphoma classification]

REAL classification

Revised European-American Lymphoma classification Hematology A new system for classifying lymphomas, proposed by the Intl Lymphoma Study group, intended to classify lymphoma that are known clinical entities; unique to the REAL classification is recognition of arbitrary nature of the distinction between lymphocytic leukemias and certain lymphomas. See Lymphoma. Cf Working Formulation.

REAL clas·si·fi·ca·tion

(rēl klas'i-fi-kā'shŭn)
A classification of lymphoma first published in 1994 based on the correlation of clinical features of lymphomas with their histopathology and immunophenotype and genotypeof neoplastic cells; groups lymphoproliferative diseases into chronic leukemia-lymphoma, nodal or extranodal lymphoma, acute leukemia lymphoma, plasma cell disorders, and Hodgkin disease.
[Revised European-American Lymphoma classification]
References in periodicals archive ?
Histological features of ocular adnexal lymphoma (REAL classification) and their association with patient morbidity and survival.
In 2001, the REAL classification system was updated by the World Health Organization, which classified Burkitt's lymphoma together with Burkitt's leukemia as a mature (peripheral) B cell neoplasm.
What is the real classification pattern in the world today?
In addition, the REAL Classification is used instead of the WHO Classification for lymphomas.
Human Lymphoma: Clinical Implications of the REAL Classification. London, England: Springer; 1999;52:1-4.
More recently, lymphoplasmacytoid lymphoma has been defined by the REAL classification as a low-grade B-cell lymphoma composed of small lymphocytes, lymphoplasmacytoid lymphocytes, and mature plasma cells and lacking features of other low-grade B-cell neoplasms.[3] This entity accounts for approximately 5% of all non-Hodgkin lymphomas and occurs in the same age group population as B-cell chronic lymphocytic leukemia, with males being affected slightly more frequently than females.