PRPH2

(redirected from RD2)
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PRPH2

A gene on chromosome 6p21.2-cen that encodes peripherin 2, a member of the tetraspanin (cell surface) protein family, which mediate signal transduction events. These events play a role in regulating cell development, activation, growth and motility. Peripherin 2 is present in the outer segment of rod and cone photoreceptor cells, and it may act as an adhesion molecule involved in stabilisation and compaction of outer
segment disks or in the maintenance of the curvature of the rim. It is essential for disk morphogenesis. 

Molecular pathology
Defects of PRPH2 are associated with a variety of retinal disorders, including adult-onset vitelliform macular dystrophy, central areolar choroidal dystrophy type 2, patterned dystrophy of retinal pigment epithelium, retinitis pigmentosa type 7, retinitis punctata albescens, as well as cone-rod dystrophy and macular degeneration.
References in periodicals archive ?
This study included a retrospective diagnostic section that screened potential diagnostic T-cell peptides from RD2 proteins and a diagnostic section that assessed the prioritized peptides for the diagnosis of active TB in patients with symptoms of tuberculosis (Figure 1).
The dependent variables in the multivariate probit model are the three R&D strategies: internal R&D (rd1), external R&D (rd2) and cooperative R&D (rd3).
Alem de sinalizar para sua preocupacao com a questao da originalidade e da lingua estrangeira, materializado no sintagma 'na lingua de origem', destaco tambem neste RD2 a polissemia do verbo 'passar' que, segundo Ferreira (2004), quer dizer: ir de um lugar a outro/ir atraves/afastar-se, cessar/ser transmitido, dentre outros sentidos.
For asphalt road and roof (RD1, RD2, and RF1), the proportions of DCOD in TCOD were in the range from 71.76% to 86.23%.
Strata-X, Inc., a subsidiary of Strata-X Ltd (TSX VENTURE:SXE), has been informed by Patriot Resources, LLC, the operator of the Vallecitos Project, that the operations on the 6-31 RD2 ST1 stepout well at Vallecitos Field, San Benito County, California, has reached a total depth of 3,952 feet.
WEDNESDAY Johnstone's Paint Trophy Rd2 - Crewe v Macclesfield, (7.30pm), Charlton v Brentford.
In this latter form, a 5-point Likert response format was incorporated, and the PS short scales was converted into a dimension with an additional new subscale for RD (RD2; Open to warm).
Cuatro dimensiones de temperamento: Busqueda de Novedades o NS (NS1: excitabilidad exploratoria; NS2: impulsividad; NS3: extravagancia; NS4: desorden), Evitacion del dano o HA (HA1: preocupacion; HA2: evitacion de riesgos; HA3: timidez; HA4: fatigabilidad), Dependencia a recompensas o RD (RD1: sentimentalismo; RD2: calidez; RD3: apego/apertura; RD4: conformidad) y Persistencia o P (P1: esforzado; P2: trabajador; P3: ambicion; P4: perfeccionismo).
PRO: 70kg: Richie Downes W Rnd 1 (Kimura) Colm Gilane, 77kg: Danny Withington W Rnd 1 (RNC) Tom Thorneycroft, 84kg: Carl Noon W Rd2 (guillotine) Chris Fields, 70kg: Aaron Wilkinson W (UD) Chris Stringer, 70kg: Mark Glover W Rd 2 (guillotine) Afnan Saeed, 77kg: Lee Chadwick W Rnd 1 (RNC) Jason Muldoon.
RD2 Construction LLC, $4,152.77 in unpaid federal taxes.
Filter Initial Efficiency Reporting Values (IERVs) with and without Bypass Site/Filter ID IERV Predicted Effective IERV with Bypass Ra1 5 5 Ra2 7 7 Ra3 11 8 Rb1 5 5 Rb2 11 8 Rc1 5 5 Rc2 6 5 Rc3 11 8 Rd1 5 5 Rd2 6 5 Rd3 11 11 Re1 5 5 Re2 7 7 Cf1 5 5 Cf2 6 5 Cf3 11 8 Cg1 7 6 Cg2 11 8 Ih 8 7 Ii 8 7 Ij 8 7 Ik 8 7 Il 8 7 Im 8 7 In addition to bypass around a filter, return duct leakage can cause the effective IERV to decline.