RANTES


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Related to RANTES: Mcp-1, Eotaxin, IP-10

RANTES

Acronymic construction for a member of the interleukin-8 superfamily of chemokines. This cytokine is an 8-kD protein that is a selective chemoattractant for memory T lymphocytes and monocytes.
[Regulated on activation, normal T expressed and secreted]

RANTES

Regulated upon Activation, Normally T-expressed, and presumably Secreted. A widely used popular name for what is officially known (per HUGO nomenclature) as CCL5, see there.
References in periodicals archive ?
Cytokine Clinical activity Endoscopic CD (CDAI) UC (Mayo) activity in UC Eotaxin 0.28, p = 0.009 ns ns GM-CSF 0.30, p = 0.005 0.33, p = 0.003 0.56, p <0.0001 IL4 0.35, p = 0.001 ns ns IL5 0.38, p <0.001 ns ns IL8 0.38, p <0.001 ns -0.38, p = 0.005 IL12(p70) 0.35, p <0.001 0.511, p <0.0001 0.49, p <0.001 IL13 ns ns ns IFN [gamma] 0.25, p = 0.019 0.45, p <0.0001 0.55, p <0.0001 RANTES 0.24, p = 0.028 ns ns TNF [alpha] 0.22, p = 0.037 ns ns hsCRP 0.40, p <0.001 0.66, p <0.0001 0.46, p <0.001 ns: not significant.
In terms of the RANTES -28C>G polymorphism, 85% of PD patients expressed C alleles and the remaining G alleles.
Interestingly, alternatively activated MDMs obtained from HIV-1 + HAART patients release lower levels of IL-6, IL-10, TNF-[alpha], IP-10, and RANTES compared to control patients after LPS stimuli.
The protein concentrations of RANTES in the plasma were measured using the commercially available DuoSet ELISA development kits (R and D Systems Inc., McKinley Place N.E., Minneapolis, USA) according to the manufacturer's protocol (RANTES catalog No.
Our results showed that ESOL inhibited the expression of MDC, RANTES, IL-8, and TARC by suppressing activation of the STAT-1, ERK, and NF-[kappa]B pathways.
mRNA expression of MCP-1, RANTES, and fractalkine in the UAP group was significantly greater than in the SAP group (P<0.05; Table 3).
We evaluated several known PLT agonists (ie, ADP, collagen, and epinephrine) for their ability to stimulate RANTES release from unfractionated PLTs in fresh WB (Figure 1).
Platelet microparticles: a transcellular delivery system for RANTES promoting monocyte recruitment on endothelium.
Ligands (RANTES, MIP-1[alpha], MIP1[beta]) of this chemokine receptor were also secreted in lesser quantity from MO/Mo of HNSCC patients, in comparison to healthy individuals.
RANTES naturally defends the body against HIV/AIDS, but cannot be used as a drug or drug candidate because it has several other biological effects, which could cause harmful inflammation.
Anti-inflammatory cytokines RANTES and TNF-[alpha], considered as natural immunity regulators, are given special consideration among others (Fryer et al., 2000a; Fryer et al., 2000b; Nickel et al., 2000).
Siddetli RSV enfeksiyonunda, RSV'li cocuklarin burun salgilari ve epitel hucrelerinde "Regulated on Activation Normal T Cell Expressed and Secreted" (RANTES) gibi kemokinlerin aktiviteleri artmistir.